Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Reasearch Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

KSR2

kinase suppressor of Ras 2

Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Gene Name: kinase suppressor of Ras 2
Family/Subfamily: Protein Kinase , Raf
Synonyms: KSR2, Kinase suppressor of ras 2, HKSR2
Target Sequences: SK605D SK605P Q6VAB6

Filtered by: None
Target
KSR2 (36)
Reactivity
Human (36)
Mouse (10)
Rat (2)
Application
IHC (12)
IHC-P (3)
WB (32)
Flo (8)
ELISA (24)
ICC (2)
IF (12)
IP (1)
Peptide-ELISA (1)
Host
rabbit (28)
mouse (8)
Isotype
IgG (24)
IgG1,k (7)
Clonality
monoclonal mc (7)
polyclonal pc (29)
Format
AP Conjugated (3)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (15)
Epitope
aa603-638 (8)
aa808-836 (8)
640-720 aa, Internal (1)
Ile694 (1)
aa411-500 (1)
aa671-720 (1)
Publications
No (36)
Showing 1-25 of 36 results

IHC-plus™ KSR2 Antibody (Ile694) LS-B9334
Rabbit Polyclonal to Human KSR2
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Anti-KSR2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Western blot analysis of Ksr2 (I694)antibody in extracts from 293 cells.

KSR2 Antibody (aa603-638) LS-C322574
Rabbit Polyclonal (IgG) to Human KSR2
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl  $590.00

KSR2 Antibody (aa603-638, Biotin) LS-C236991
Rabbit Polyclonal (IgG) to Human KSR2
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl  $740.00

KSR2 Antibody (aa603-638, FITC) LS-C236992
Rabbit Polyclonal (IgG) to Human KSR2
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl  $740.00

KSR2 Antibody (aa603-638, PE) LS-C236993
Rabbit Polyclonal (IgG) to Human KSR2
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl 0.55mg/ml  $740.00

KSR2 Antibody (aa603-638, APC) LS-C236989
Rabbit Polyclonal (IgG) to Human KSR2
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl  $740.00

KSR2 Antibody (aa603-638, AP) LS-C236990
Rabbit Polyclonal (IgG) to Human KSR2
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl  $740.00

KSR2 Antibody (aa603-638, Azide-free, HRP) LS-C248681
Rabbit Polyclonal (IgG) to Human KSR2
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

KSR2 Antibody LS-C760873
Rabbit Polyclonal to Human KSR2
Mouse, Human
ICC, IF, IHC, IP, WB
Unconjugated
30µl 1mg/ml  $205.00; 100µl 1mg/ml  $245.00; 200µl 1mg/ml  $305.00
Immunohistochemical analysis of KSR2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Immunofluorescent analysis of KSR2 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with Alexa Fluor 647-conjugated secondary antibody (red) in PBS at room temperature in the dark.

KSR2 Antibody (640-720 aa, Internal) LS-C384278
Rabbit Polyclonal (IgG) to Human KSR2
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

KSR2 Antibody (aa603-638) LS-C165650
Rabbit Polyclonal to Human KSR2
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
KSR2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
KSR2 Antibody western blot of 293,K562,HepG2,HeLa cell line lysates (35 ug/lane). The KSR2 antibody detected the KSR2 protein (arrow).

KSR2 Antibody LS-C674264
Rabbit Polyclonal (IgG) to Human KSR2
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image at a dilution of 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of Hela cells at a dilution of 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .

KSR2 Antibody LS-C808453
Rabbit Polyclonal (IgG) to Human KSR2
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image

KSR2 Antibody (aa411-500) LS-C308700
Mouse Monoclonal (IgG1,k) to Human KSR2
Human
ELISA, IF, WB
Unconjugated
100µg  $560.00

KSR2 Antibody (Biotin) LS-C522779
Mouse Monoclonal (IgG1,k) to Human KSR2
Human
ELISA, IF, WB
Biotin Conjugated
100µl  $710.00

KSR2 Antibody (FITC) LS-C532823
Mouse Monoclonal (IgG1,k) to Human KSR2
Human
ELISA, IF, WB
FITC Conjugated
100µl  $710.00

KSR2 Antibody (APC) LS-C514564
Mouse Monoclonal (IgG1,k) to Human KSR2
Human
ELISA, IF, WB
APC Conjugated
100µl  $710.00

KSR2 Antibody (PE) LS-C651022
Mouse Monoclonal (IgG1,k) to Human KSR2
Human
ELISA, IF, WB
PE Conjugated
100µl  $710.00

KSR2 Antibody LS-C416269
Rabbit Polyclonal to Human KSR2
Mouse, Human
ICC, IF, WB
Unconjugated
100µg  $305.00
Western blot of 293 cell lysate using KSR2 Antibody

KSR2 Antibody (aa671-720) LS-C119110
Rabbit Polyclonal (IgG) to Human KSR2
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunofluorescence analysis of HeLa cells, using KSR2 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from 293 cells, using KSR2 Antibody. The lane on the right is blocked with the synthesized peptide.

KSR2 Antibody (aa808-836) LS-C322571
Rabbit Polyclonal (IgG) to Mouse KSR2
Mouse, Human
ELISA, WB
Unconjugated
200µl  $590.00

KSR2 Antibody (aa808-836, FITC) LS-C236996
Rabbit Polyclonal (IgG) to Mouse KSR2
Human
ELISA, WB
FITC Conjugated
200µl  $740.00

KSR2 Antibody (aa808-836, APC) LS-C236994
Rabbit Polyclonal (IgG) to Mouse KSR2
Human
ELISA, WB
APC Conjugated
200µl  $740.00

KSR2 Antibody (aa808-836, AP) LS-C236995
Rabbit Polyclonal (IgG) to Mouse KSR2
Human
ELISA, WB
AP Conjugated
200µl  $740.00

KSR2 Antibody (aa808-836, PE) LS-C236999
Rabbit Polyclonal (IgG) to Mouse KSR2
Human
ELISA, WB
PE Conjugated
200µl  $740.00
Showing 1-25 of 36 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).