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In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Gene Name: | keratin associated protein 3-3 |
Synonyms: | KRTAP3-3, Keratin associated protein 3-3, Keratin-associated protein 3-3, Keratin-associated protein 3.3, KRTAP3.3, KAP3.3 |
Target Sequences: | Q9D7P0 Q9D7P0 |
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