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The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.
Gene Name: | keratin 83 |
Family/Subfamily: | Keratin , not assigned-Keratin |
Synonyms: | KRT83, Hard keratin, type II, 3, HB3, Hair keratin K2.10, K83, Keratin 83, Keratin, hair, basic, 3, Keratin, type II cuticular Hb3, HHb3, Keratin-83, KRTHB3, Type-II keratin Kb23, Hb-3, Type II hair keratin Hb3 |
Target Sequences: | X99141 CAA67578.1 P78385 |
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