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The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Gene Name: | keratin 3 |
Family/Subfamily: | Keratin , not assigned-Keratin |
Synonyms: | KRT76, 65 kDa cytokeratin, CK-3, Cytokeratin 2e, Cytokeratin-3, Ck 2e, Cytokeratin 3, Keratin-3, Keratin 3, Krt2e, KRT3, Type-II keratin Kb3, CK3, K3 |
Target Sequences: | NM_015848 NP_056932.2 Q01546 |
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