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KRT20 / CK20 / Cytokeratin 20

keratin 20

KRT20 / CK20 / Cytokeratin 20 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.

Gene Name: keratin 20
Family/Subfamily: Keratin , not assigned-Keratin
Synonyms: KRT20, Cytokeratin-20, Cytokeratin 20, CK20, K20, Keratin 20, Keratin-20, KRT21, CK-20, Protein IT
Target Sequences: X73502 CAA51914.1 P35900

Publications (1)

1
Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization. Sixia Huang, Paola Kuri, Yann Aubert, Megan Brewster, Ning Li, Olivia Farrelly, Gabriella Rice, Hyunjin Bae, Stephen Prouty, Tzvete Dentchev, Wenqin Luo, Brian C Capell, Panteleimon Rompolas. Cell stem cell. 2021 September;28:1582-1596.e6. [Full Text Article] [PubMed:34102139] [PMC:PMC8528178]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).