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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KNG1 / Kininogen / Bradykinin

kininogen 1

1 Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.

Gene Name: kininogen 1
Synonyms: KNG1, Bradykinin, Flaujeac factor deficiency, Fitzgerald factor, Kininogen 1, Kininogen-1, Kininogen, BDK, HMWK, KNG
Target Sequences: NM_000893 NP_000884.1 P01042

Filtered by: None
Target
KNG1 / Kininogen / Bradykinin (94)
Reactivity
Human (87)
Mouse (28)
Rat (2)
Chimpanzee (9)
Dog (4)
Gibbon (6)
Horse (4)
Monkey (13)
Orangutan (6)
Pig (8)
Application
IHC (55)
IHC-P (12)
WB (87)
Flo (7)
ELISA (25)
ICC (6)
ID (1)
IF (2)
IP (2)
Peptide-ELISA (2)
Host
rabbit (83)
mouse (8)
goat (3)
Isotype
IgG (32)
IgG,k (1)
IgG1 (2)
IgG2a (1)
IgG2a,k (1)
Clonality
monoclonal mc (7)
polyclonal pc (87)
Clone
2B5 (1)
4A1 (1)
C11C1 (1)
Format
AP Conjugated (2)
APC (4)
APC Conjugated (6)
Azide-free (2)
Biotin Conjugated (13)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (13)
HRP Conjugated (10)
PE Conjugated (6)
Unconjugated (36)
Epitope
aa22-379 (10)
aa390-644 (10)
aa138-166 (8)
C-Terminus (4)
aa251-300 (4)
aa40-89 (4)
300-380 aa, Internal (1)
aa1-416 (1)
aa19-210 (1)
aa227-259 (1)
aa268-279 (1)
aa378-430 (1)
aa58-70 (1)
Publications
No (94)
Showing 1-25 of 94 results

KNG1 / Kininogen / Bradykinin Antibody (aa1-416) IHC-plus™ LS-B10750
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ICC IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-KNG1 / Kininogen / Bradykinin antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
Immunofluorescence of paraformaldehyde-fixed HeLa using Kininogen-1 antibody at 1:200 dilution.

KNG1 / Kininogen / Bradykinin Antibody LS-C62058
Mouse Monoclonal (IgG,k) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA WB
Unconjugated
100µl 1mg/ml  $305.00
Western blot Image

KNG1 / Kininogen / Bradykinin Antibody (aa251-300) IHC-plus™ LS-B8101
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Mouse, Horse, Human, Monkey
IHC IHC-P WB
Unconjugated
100µl  $485.00
Anti-Kininogen / Bradykinin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
KNG1 / Kininogen antibody Western blot of Fetal Liver lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

KNG1 / Kininogen / Bradykinin Antibody (aa227-259) LS-C407867
Rabbit Polyclonal to Mouse KNG1 / Kininogen / Bradykinin
Mouse
IHC IHC-P WB
Unconjugated
100µg  $355.00
Kininogen 1 antibody IHC-paraffin. IHC(P): Mouse Kidney Tissue.
Kininogen 1 antibody Western blot. All lanes: Anti Kininogen 1 at 0.5 ug/ml. Lane 1: Mouse Lung Tissue Lysate at 50 ug. Lane 2: Mouse Testis Tissue Lysate at 50 ug. Lane 3: Mouse Liver Tissue Lysate at 50 ug. Lane 4: HEPA Whole Cell Lysate at 40 ug. Lane 5: NEURO Whole Cell Lysate at 40 ug. Predicted band size: 73 kD. Observed band size: 73 kD.

KNG1 / Kininogen / Bradykinin Antibody (300-380 aa, Internal) LS-C380542
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Cleaved-Kininogen-1 HC (K380) antibody

KNG1 / Kininogen / Bradykinin Antibody (aa138-166) LS-C322537
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA Flo IHC WB
Unconjugated
200µl  $590.00

KNG1 / Kininogen / Bradykinin Antibody (aa138-166, Biotin) LS-C520331
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA Flo IHC WB
Biotin Conjugated
200µl  $740.00

KNG1 / Kininogen / Bradykinin Antibody (aa138-166, FITC) LS-C530495
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
Flo IHC WB
FITC Conjugated
200µl  $740.00

KNG1 / Kininogen / Bradykinin Antibody (aa138-166, APC) LS-C261518
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA Flo IHC WB
APC Conjugated
200µl  $740.00

KNG1 / Kininogen / Bradykinin Antibody (aa138-166, PE) LS-C261520
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA Flo IHC WB
PE Conjugated
200µl  $740.00

KNG1 / Kininogen / Bradykinin Antibody (aa138-166, AP) LS-C261519
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA Flo IHC WB
AP Conjugated
200µl  $740.00

KNG1 / Kininogen / Bradykinin Antibody (aa58-70) IHC-plus™ LS-B10584
Goat Polyclonal to Human KNG1 / Kininogen / Bradykinin
Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-KNG1 / Kininogen / Bradykinin antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
KNG1 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

KNG1 / Kininogen / Bradykinin Antibody (aa138-166) IHC-plus™ LS-B10444
Rabbit Polyclonal to Human KNG1 / Kininogen / Bradykinin
Human
Flo IHC IHC-P WB
Unconjugated
200µl  $425.00
Anti-KNG1 / Kininogen / Bradykinin antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot of KNG1 (arrow) using rabbit polyclonal KNG1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the KNG1 gene.

KNG1 / Kininogen / Bradykinin Antibody IHC-plus™ LS-B11411
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA IHC IHC-P WB
Unconjugated
100µg  $565.00
Anti-KNG1 / Kininogen / Bradykinin antibody IHC staining of human tonsil, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Kininogen-1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to rabbit IgG at 1:10000 dilution. Predicted band size: 71 kDa. Observed band size: 71 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KNG1 / Kininogen / Bradykinin Antibody (HRP) LS-C211440
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA IHC IHC-P WB
HRP Conjugated
50µg  $285.00; 100µg 0.4mg/ml  $385.00
Anti-KNG1 / Kininogen / Bradykinin antibody IHC staining of human tonsil, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Kininogen-1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to rabbit IgG at 1:10000 dilution. Predicted band size: 71 kDa. Observed band size: 71 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KNG1 / Kininogen / Bradykinin Antibody (Biotin) LS-C211442
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA IHC IHC-P WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00
Anti-KNG1 / Kininogen / Bradykinin antibody IHC staining of human tonsil, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Kininogen-1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to rabbit IgG at 1:10000 dilution. Predicted band size: 71 kDa. Observed band size: 71 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KNG1 / Kininogen / Bradykinin Antibody (FITC) LS-C211441
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA IHC IHC-P WB
FITC Conjugated
50µg  $285.00; 100µg  $385.00
Anti-KNG1 / Kininogen / Bradykinin antibody IHC staining of human tonsil, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Kininogen-1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to rabbit IgG at 1:10000 dilution. Predicted band size: 71 kDa. Observed band size: 71 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KNG1 / Kininogen / Bradykinin Antibody (clone 2B5) LS-C83339
Mouse Monoclonal [clone 2B5] (IgG1) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA WB
Unconjugated
200µg  $475.00
Western blots to detect human HMWK light chain.

KNG1 / Kininogen / Bradykinin Antibody (aa268-279) LS-C205032
Goat Polyclonal to Human KNG1 / Kininogen / Bradykinin
Human, Monkey
Peptide-ELISA WB
Unconjugated
100µg 0.5mg/ml  $405.00
KNG1 antibody (0.03 ug/ml) staining of Albumin-depleted Plasma lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

KNG1 / Kininogen / Bradykinin Antibody LS-C310839
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Mouse, Human
WB
Unconjugated
100µg  $605.00

KNG1 / Kininogen / Bradykinin Antibody (aa40-89) LS-C187226
Rabbit Polyclonal to Human KNG1 / Kininogen / Bradykinin
Dog, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
Western blot of Human Placenta . KNG1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KNG1 / Kininogen / Bradykinin Antibody LS-C755107
Mouse Monoclonal (IgG2a) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA IF IHC WB
Unconjugated
100µg  $375.00

KNG1 / Kininogen / Bradykinin Antibody LS-C755106
Rabbit Polyclonal (IgG) to Human KNG1 / Kininogen / Bradykinin
Human
ELISA IF IHC WB
Unconjugated
100µg  $375.00

KNG1 / Kininogen / Bradykinin Antibody (aa22-379) LS-C372693
Rabbit Polyclonal to Mouse KNG1 / Kininogen / Bradykinin
Mouse, Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $515.00; 10ml 0.5mg/ml  $2,040.00
Immunohistochemistry - Paraffin Image
Western blot of KNG1 / Kininogen / Bradykinin antibody.

KNG1 / Kininogen / Bradykinin Antibody LS-C663762
Rabbit Polyclonal to Human KNG1 / Kininogen / Bradykinin
Pig, Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $495.00; 10ml 0.5mg/ml  $1,980.00
DAB staining on IHC-P. Samples: Human Tissue
Western Blot; Sample: Porcine Kidney lysate; Primary Ab: 1µg/ml Rabbit Anti-Human HMWK Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Showing 1-25 of 94 results

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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