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KLRC1 / NKG2A / CD159a

killer cell lectin-like receptor subfamily C, member 1

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene Name: killer cell lectin-like receptor subfamily C, member 1
Synonyms: KLRC1, CD159a antigen, NK cell receptor A, Natural killer cell lectin, NKG2, NKG2-A, NKG2A, C-lectin type II protein, CD159A, Natural killer group protein 2, NKG2-B
Target Sequences: NM_002259 NP_002250.1 P26715

☰ Filters
Products
Proteins (14)
Over-Expression Lysate (9)
Recombinant (5)
KLRC1 / NKG2A / CD159a (14)
No (14)
8His, N-terminus (2)
GST (1)
GST, N-terminus (1)
His,N-terminus (1)
Myc-DDK (Flag) (9)
Human (9)
Mouse (1)
293T Cells (5)
HEK 293 Cells (5)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (3)
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Human Cells
8His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
16.5kD
10 µg/$233; 50 µg/$277; 500 µg/$725; 1 mg/$1,113
KLRC1 / NKG2A / CD159a Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
KLRC1 / NKG2A / CD159a Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
24 kDa
100 µg/$494
KLRC1 / NKG2A / CD159a Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
24 kDa
100 µg/$494
KLRC1 / NKG2A / CD159a Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.1 kDa
100 µg/$494
KLRC1 / NKG2A / CD159a Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.1 kDa
100 µg/$494
KLRC1 / NKG2A / CD159a Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
24 kDa
20 µg/$150
KLRC1 / NKG2A / CD159a Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
24 kDa
20 µg/$150
KLRC1 / NKG2A / CD159a Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.1 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
26.1 kDa
20 µg/$150
KLRC1 / NKG2A / CD159a Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.1 kDa
20 µg/$150
KLRC1 / NKG2A / CD159a Protein - 12.5% SDS-PAGE of human KLRC1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
52.7 kDa
10 µg/$479; 25 µg/$670
Select
Mammalian Cells
8His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
16.5 kDa
10 µg/$233; 50 µg/$277
Select
HEK 293 Cells
His,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
19.6 kDa
50 µg/$721
Viewing 1-14 of 14 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).