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KLF2

Kruppel-like factor 2

Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).

Gene Name:	Kruppel-like factor 2
Synonyms:	KLF2, Krueppel-like factor 2, Kruppel-like factor LKLF, Kruppel-like factor 2 (lung), Lung krueppel-like factor, LKLF
Target Sequences:	AF123344 AAD25076.1 Q9Y5W3

Publications (6)

Disturbed shear stress reduces Klf2 expression in arterial-venous fistulae in vivo. Yamamoto K, Protack CD, Kuwahara G, Tsuneki M, Hashimoto T, Hall MR, Assi R, Brownson KE, Foster TR, Bai H, Wang M, Madri JA, Dardik A. Physiological reports. 2015 3: (IHC, IF; Mouse) [Full Text Article] [PubMed:25780089] [PMC:PMC4393175] Related Antibodies: LS-B5627.

SIV/SHIV Infection Triggers Vascular Inflammation, Diminished Expression of Krüppel-like Factor 2 and Endothelial Dysfunction. Panigrahi S, Freeman ML, Funderburg NT, Mudd JC, Younes SA, Sieg SF, Zidar DA, Paiardini M, Villinger F, Calabrese LH, Ransohoff RM, Jain MK, Lederman MM. The Journal of infectious diseases. 2016 May;213:1419-27. (Human) [Full Text Article] [PubMed:26671887] [PMC:PMC4813739] Related Antibodies: LS-B4570.

Integrated proteomics and metabolomics analysis reveals differential lipid metabolism in human umbilical vein endothelial cells under high and low shear stress. Gabriela Venturini, Pamella Araujo Malagrino, Kallyandra Padilha, Leonardo Yuji Tanaka, Francisco Rafael Laurindo, Rafael Dariolli, Valdemir Melechco Carvalho, Karina Helena Morais Cardozo, Jose Eduardo Krieger, Alexandre da Costa Pereira. American journal of physiology. Cell physiology. 2019 August;317:C326-C338. [Full Text Article] [PubMed:31067084] Related Antibodies: LS-B4570.

Reduced patency in left-sided arteriovenous grafts in a porcine model. Shirley Liu, Tun Wang, Juan Wang, Toshihiko Isaji, Shun Ono, Arash Fereydooni, Ryosuke Taniguchi, Yutaka Matsubara, Laura E Niklason, Alan Dardik. Journal of vascular surgery. 2020 July;72:305-317.e6. [Full Text Article] [PubMed:31699515] [PMC:PMC7196525] Related Antibodies: LS-B5627.

SARS-CoV-2 Spike Protein Destabilizes Microvascular Homeostasis. Soumya Panigrahi, Tamal Goswami, Brian Ferrari, Christopher J Antonelli, Douglas A Bazdar, Hannah Gilmore, Michael L Freeman, Michael M Lederman, Scott F Sieg. Microbiology spectrum. 2021 December;9:e0073521. [Full Text Article] [PubMed:34935423] [PMC:PMC8693925] Related Antibodies: LS-B4570.

Human ß-Defensin-3 is Associated With Platelet-Derived Extracellular Vesicles and is a Potential Contributor to Endothelial Dysfunction. Soumya Panigrahi, Santosh K Ghosh, Brian Ferrari, Jonathan M Wyrick, Eugene A Podrez, Aaron Weinberg, Scott F Sieg. Frontiers in molecular biosciences. 2022 April;9:824954. [Full Text Article] [PubMed:35355507] [PMC:PMC8959671] Related Antibodies: LS-B4570.

Rat KLF2 (Sandwich ELISA) ELISA Kit - LS-F8680

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$893

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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