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KLC1 / Kinesin Light Chain 1

kinesin light chain 1

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.

Gene Name: kinesin light chain 1
Synonyms: KLC1, HKLC1B, HKLC1N, KNS2, Kinesin 2, Kinesin 2 60/70kDa, KLC, HKLC1J, HKLC1S, Kinesin light chain, Kinesin light chain 1, KLC 1, KNS2A, HKLC1G, HKLC1P, HKLC1R
Target Sequences: NM_005552 NP_005543.2 Q07866

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Proteins (4)
Over-Expression Lysate (4)
KLC1 / Kinesin Light Chain 1 (4)
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HEK 293 Cells (2)
KLC1 / Kinesin Light Chain 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
63.6 kDa
100 µg/$494
KLC1 / Kinesin Light Chain 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
65.1 kDa
100 µg/$710
KLC1 / Kinesin Light Chain 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
63.6 kDa
20 µg/$150
KLC1 / Kinesin Light Chain 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
65.1 kDa
20 µg/$215
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).