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KIR2DS5

Killer Cell Immunoglobulin-like Receptor, Two Domains, Short Cytoplasmic Tail, 5

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene Name: Killer Cell Immunoglobulin-like Receptor, Two Domains, Short Cytoplasmic Tail, 5
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: KIR2DS5, CD158g antigen, MHC class I NK cell receptor, NKAT9, NKAT-9, CD158G
Target Sequences: NM_014513 NP_055328.2 Q14953

☰ Filters
Antibodies (8)
Proteins (3)
ELISA Kits (1)
Custom (1)
Over-Expression Lysate (2)
Primary (8)
Recombinant (1)
KIR2DS5 (12)
Human (9)
Mouse (2)
WB (4)
ELISA (5)
IF (1)
Peptide-ELISA (1)
rabbit (8)
IgG (5)
polyclonal pc (8)
96-Well Strip Plate (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (5)
Internal (1)
No (12)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
KIR2DS5 Antibody - Immunofluorescence staining of HepG2 cells diluted at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The Secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
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KIR2DS5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
Select
KIR2DS5 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
KIR2DS5 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
KIR2DS5 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
KIR2DS5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
KIR2DS5 Antibody - Western blot analysis of KIR2DS5 using LOVO cells whole cells lysates
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KIR2DS5 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KIR2DS5 Antibody - Western blot analysis of CD158g expression in HeLa (A); SP2/0 (B); NIH3T3 (C) whole cell lysates.
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KIR2DS5 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$299
KIR2DS5 Antibody - Anti-CD158g Antibody at 1:1000 dilution + HeLa whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 34 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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KIR2DS5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µl/$386
KIR2DS5 Protein
Select
GST
59.84kDa
10 µg/$479; 25 µg/$670
KIR2DS5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
33.5 kDa
20 µg/$150
KIR2DS5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
33.5 kDa
100 µg/$494
KIR2DS5 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
1 Plate/$783
Viewing 1-12 of 12 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).