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KIR2DS2 / CD158j

Killer Cell Immunoglobulin-like Receptor, Two Domains, Short Cytoplasmic Tail, 2

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene represents a haplotype-specific family member that encodes a protein with a short cytoplasmic tail. Alternative splicing results in multiple transcript variants.

Gene Name: Killer Cell Immunoglobulin-like Receptor, Two Domains, Short Cytoplasmic Tail, 2
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: KIR2DS2, 1060P11.9.2, 183ActI, CD158j antigen, CD158J, Killer-cell Ig-like receptor, MHC class I NK cell receptor, NK receptor 183 ActI, p58 KIR, p58 NK receptor CL-49, Cl-49, NKAT-5, NKAT5
Target Sequences: NM_012312 NP_036444.1 P43631

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Products
Antibodies (24)
Primary (24)
KIR2DS2 / CD158j (24)
Human (24)
IHC (7)
IHC-P (2)
WB (20)
ELISA (8)
ICC (1)
IF (2)
rabbit (24)
IgG (10)
polyclonal pc (24)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (6)
aa22-304 (8)
aa39-65 (6)
aa43-92 (4)
No (24)
KIR2DS2 / CD158j Antibody - KIR2DS2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skin carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa39-65) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa39-65) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa39-65) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa39-65) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa39-65) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa39-65) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
KIR2DS2 / CD158j Antibody - Immunocytochemistry of KIR2DS2 in Hek293 cells with KIR2DS2 antibody at 5 ug/mL.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, WB
Unconjugated
0.1 mg/$460
KIR2DS2 / CD158j Antibody - Immunohistochemistry image of paraffin-embedded human lymph node tissue at a dilution of 1:100
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
KIR2DS2 / CD158j Antibody - Western blot of recombinant KIR2DS2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa22-304) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
KIR2DS2 / CD158j Antibody - Western blot of recombinant KIR2DS2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa22-304) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
KIR2DS2 / CD158j Antibody - Western blot of recombinant KIR2DS2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa22-304) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
KIR2DS2 / CD158j Antibody - Western blot of recombinant KIR2DS2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa22-304) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
KIR2DS2 / CD158j Antibody - Western blot of recombinant KIR2DS2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa22-304) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
KIR2DS2 / CD158j Antibody - Western blot of recombinant KIR2DS2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa22-304) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
KIR2DS2 / CD158j Antibody - Western blot of recombinant KIR2DS2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa22-304) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
KIR2DS2 / CD158j Antibody - Western blot of recombinant KIR2DS2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa22-304) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
KIR2DS2 / CD158j Antibody - CD158b / KIR2DS2 antibody Western Blot of A549.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa43-92) Antibody
Human
WB
Unconjugated
100 µl/$424
KIR2DS2 / CD158j Antibody - CD158b / KIR2DS2 antibody Western Blot of A549.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa43-92) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
KIR2DS2 / CD158j Antibody - CD158b / KIR2DS2 antibody Western Blot of A549.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa43-92) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
KIR2DS2 / CD158j Antibody - CD158b / KIR2DS2 antibody Western Blot of A549.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIR2DS2 / CD158j Rabbit anti-Human Polyclonal (aa43-92) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).