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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KIR2DS1 / CD158a

killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene Name: killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: KIR2DS1, CD158H, CD158h antigen, EB6ActI, EB6ActII, KIR2DL1-KIR2DS1, p50.1, CD158A
Target Sequences: NM_014512 NP_055327.1 Q14954

Filtered By: None
Target
KIR2DS1 / CD158a (12)
Reactivity
Human (12)
Application
WB (8)
ELISA (11)
Host
rabbit (12)
Isotype
IgG (11)
Clonality
polyclonal pc (12)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (3)
Epitope
aa151-180 (8)
aa22-245 (4)
Publications
No (12)
Showing 1-12 of 12 results

KIR2DS1 / CD158a Antibody (aa151-180) LS-C329732
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA WB
Unconjugated
200µl  $530.00

KIR2DS1 / CD158a Antibody (aa151-180, Biotin) LS-C215426
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

KIR2DS1 / CD158a Antibody (aa151-180, FITC) LS-C215427
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA WB
FITC Conjugated
200µl  $680.00

KIR2DS1 / CD158a Antibody (aa151-180, AP) LS-C215424
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA WB
AP Conjugated
200µl  $680.00

KIR2DS1 / CD158a Antibody (aa151-180, APC) LS-C215425
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA WB
APC Conjugated
200µl  $680.00

KIR2DS1 / CD158a Antibody (aa151-180, Azide-free, HRP) LS-C215428
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

KIR2DS1 / CD158a Antibody (aa151-180, PE) LS-C215429
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA WB
PE Conjugated
200µl  $680.00

KIR2DS1 / CD158a Antibody (aa22-245) LS-C371421
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA
Unconjugated
50µg  $285.00; 100µg  $385.00

KIR2DS1 / CD158a Antibody (aa22-245, HRP) LS-C371422
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

KIR2DS1 / CD158a Antibody (aa22-245, Biotin) LS-C371424
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

KIR2DS1 / CD158a Antibody (aa22-245, FITC) LS-C371423
Rabbit Polyclonal (IgG) to Human KIR2DS1 / CD158a
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00

KIR2DS1 / CD158a Antibody (aa151-180) LS-C165529
Rabbit Polyclonal to Human KIR2DS1 / CD158a
Human
WB
Unconjugated
400µl  $305.00
KIR2DS1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The KIR2DS1 antibody detected the KIR2DS1 protein (arrow).
KIR2DS1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The KIR2DS1 antibody detected the KIR2DS1 protein (arrow).
Showing 1-12 of 12 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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