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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KIR2DL1 / CD158a

killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene Name: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: KIR2DL1, 47.11, Cl-42, MHC class I NK cell receptor, NKAT-1, p58 NK receptor CL-42/47.11, NKAT, NKAT1, p58.1, CD158A, CD158a antigen, Killer Ig receptor, KIR-K64, KIR221
Target Sequences: NM_014218 NP_055033.2 P43626

Filtered By: None
Target
KIR2DL1 / CD158a (46)
Reactivity
Human (46)
Mouse (1)
Gibbon (3)
Monkey (4)
Orangutan (3)
Application
IHC (11)
IHC-P (1)
WB (34)
Flo (14)
ELISA (16)
Func (2)
IP (11)
Host
rabbit (33)
mouse (13)
Isotype
IgG (22)
IgG1 (11)
IgG2a (1)
IgG2a,k (1)
Clonality
monoclonal mc (13)
polyclonal pc (33)
Clone
2F9 (1)
NKVFS1 (1)
Format
AP Conjugated (2)
APC (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (7)
HRP Conjugated (5)
PE Conjugated (5)
Unconjugated (16)
Epitope
aa22-348 (8)
C-Terminus (4)
131-180 aa, Internal (1)
Publications
No (46)
Showing 1-25 of 46 results

KIR2DL1 / CD158a Antibody (clone 2F9) LS-C93763
Mouse Monoclonal [clone 2F9] (IgG2a) to Human KIR2DL1 / CD158a
Human
ELISA IP WB
Unconjugated
50µl 1mg/ml  $315.00
Recombinant human protein KIR2DL1, KIR2DL3, KIR2DS4 and KIR2DL4 (each 50 ng per well) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KIR2DL1 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1: KIR2DL1; Lane 2: KIR2DL3; Lane 3: KIR2DS4; Lane 4: KIR2DL4.
Recombinant human protein KIR2DL1, KIR2DL3, KIR2DS4 and KIR2DL4 (each 50 ng per well) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KIR2DL1 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1: KIR2DL1; Lane 2: KIR2DL3; Lane 3: KIR2DS4; Lane 4: KIR2DL4.

KIR2DL1 / CD158a Antibody LS-C192811
Rabbit Polyclonal to Human KIR2DL1 / CD158a
Human
IHC WB
Unconjugated
100µl  $385.00
Western blot of extracts of HepG2 cell lines, using KIR2DL1 antibody.
Western blot of extracts of HepG2 cell lines, using KIR2DL1 antibody.

KIR2DL1 / CD158a Antibody (aa22-348) LS-C295031
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $495.00; 10ml 0.5mg/ml  $1,980.00
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL1 / CD158a Antibody (aa22-348, HRP) LS-C709825
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $335.00; 1ml  $650.00; 10ml  $2,580.00
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL1 / CD158a Antibody (aa22-348, Biotin) LS-C297052
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
IHC WB
Biotin Conjugated
100µl 0.5mg/ml  $415.00
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL1 / CD158a Antibody (aa22-348, FITC) LS-C303106
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
IHC WB
FITC Conjugated
100µl 0.5mg/ml  $435.00
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL1 / CD158a Antibody (aa22-348, Cy3) LS-C700802
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $345.00; 200µl  $425.00; 1ml  $995.00; 10ml  $3,975.00
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL1 / CD158a Antibody (aa22-348, APC) LS-C739767
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
IHC WB
APC Conjugated
20µl  $225.00; 100µl  $295.00; 200µl  $355.00; 1ml  $740.00
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL1 / CD158a Antibody (aa22-348, PE) LS-C723885
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
IHC WB
PE Conjugated
20µl  $205.00; 100µl  $275.00; 200µl  $315.00; 1ml  $590.00; 10ml  $2,385.00
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL1 / CD158a Antibody (aa22-348, APC, Cy7) LS-C732876
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
IHC WB
APC, Cy7 Conjugated
20µl  $285.00; 100µl  $435.00; 200µl  $590.00; 1ml  $1,485.00; 10ml  $5,970.00
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL1 / CD158a.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL1 / CD158a Antibody (clone NKVFS1, Azide-free) LS-C16153
Mouse Monoclonal [clone NKVFS1] (IgG1) to Human KIR2DL1 / CD158a
Human
ELISA Flo Func IP WB
Unconjugated, Azide-free
1000µg  $1,095.00

KIR2DL1 / CD158a Antibody LS-C16155
Mouse Monoclonal (IgG1) to Human KIR2DL1 / CD158a
Human
ELISA Flo Func IP WB
Unconjugated
500µg 1mg/ml  $740.00

KIR2DL1 / CD158a Antibody LS-C16151
Mouse Monoclonal (IgG1) to Human KIR2DL1 / CD158a
Human
ELISA Flo IP WB
Unconjugated
100µg  $445.00

KIR2DL1 / CD158a Antibody (HRP) LS-C547518
Mouse Monoclonal (IgG1) to Human KIR2DL1 / CD158a
Human
ELISA Flo IP WB
HRP Conjugated
100µl  $605.00

KIR2DL1 / CD158a Antibody (Biotin) LS-C527416
Mouse Monoclonal (IgG1) to Human KIR2DL1 / CD158a
Human
ELISA Flo IP WB
Biotin Conjugated
100µl  $605.00

KIR2DL1 / CD158a Antibody (FITC) LS-C537389
Mouse Monoclonal (IgG1) to Human KIR2DL1 / CD158a
Human
ELISA Flo IP WB
FITC Conjugated
100µl  $605.00

KIR2DL1 / CD158a Antibody (PE) LS-C655562
Mouse Monoclonal (IgG1) to Human KIR2DL1 / CD158a
Human
ELISA Flo IP WB
PE Conjugated
100µl  $605.00

KIR2DL1 / CD158a Antibody (AP) LS-C509396
Mouse Monoclonal (IgG1) to Human KIR2DL1 / CD158a
Human
ELISA IP WB
AP Conjugated
100µl  $605.00

KIR2DL1 / CD158a Antibody (FITC) LS-C16156
Mouse Monoclonal (IgG1) to Human KIR2DL1 / CD158a
Human
ELISA Flo IP WB
FITC Conjugated
100µg  $575.00

KIR2DL1 / CD158a Antibody LS-C673248
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
ELISA IHC IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

KIR2DL1 / CD158a Antibody LS-C8360
Mouse Monoclonal (IgG2a,k) to Human KIR2DL1 / CD158a
Human
ELISA IP WB
Unconjugated
50µl 0.5mg/ml  $375.00; 100µl  $435.00

KIR2DL1 / CD158a Antibody LS-C335171
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Mouse, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cell lines, using KIR2DL1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
Western blot analysis of extracts of various cell lines, using KIR2DL1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.

KIR2DL1 / CD158a Antibody LS-C743173
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
ELISA WB
Unconjugated
50µg 1mg/ml  $265.00; 100µg 1mg/ml  $325.00
Western Blot analysis of extracts from NIH-3T3 cells using KIR2DL1 Antibody.
Western Blot analysis of extracts from NIH-3T3 cells using KIR2DL1 Antibody.

KIR2DL1 / CD158a Antibody (131-180 aa, Internal) LS-C387699
Rabbit Polyclonal (IgG) to Human KIR2DL1 / CD158a
Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of CD158a antibody
Western blot of CD158a antibody
Western blot of CD158a antibody
Western blot of CD158a antibody

KIR2DL1 / CD158a Antibody LS-C487903
Rabbit Polyclonal to Human KIR2DL1 / CD158a
Human
Flo
Unconjugated
50µl  $275.00; 100µl  $355.00
Showing 1-25 of 46 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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