KIND2 / FERMT2

fermitin family member 2

Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading; this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.

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Products

Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

KIND2 / FERMT2 (6)

Publications

No (6)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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KIND2 / FERMT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125363

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.5 kDa

Price:

100 µg/$710

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KIND2 / FERMT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115041

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.7 kDa

Price:

100 µg/$494

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Human KIND2 / FERMT2 Protein (Recombinant GST) (Full Length) - LS-G32432

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

100.54 kDa

Price:

10 µg/$479; 25 µg/$670

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Human KIND2 / FERMT2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69169

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.7 kDa

Price:

20 µg/$1,107

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Human KIND2 / FERMT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83981

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.7 kDa

Price:

20 µg/$150

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Human KIND2 / FERMT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83979

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.5 kDa

Price:

20 µg/$215

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