KIF7

kinesin family member 7

Essential for hedgehog signaling regulation: acts as both a negative and positive regulator of sonic hedgehog (Shh) and Indian hedgehog (Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and -independent mechanisms (PubMed:21633164). Involved in the regulation of microtubular dynamics. Required for proper organization of the ciliary tip and control of ciliary localization of SUFU-GLI2 complexes (By similarity). Required for localization of GLI3 to cilia in response to Shh. Negatively regulates Shh signaling by preventing inappropriate activation of the transcriptional activator GLI2 in the absence of ligand. Positively regulates Shh signaling by preventing the processing of the transcription factor GLI3 into its repressor form. In keratinocytes, promotes the dissociation of SUFU-GLI2 complexes, GLI2 nuclear translocation and Shh signaling activation (By similarity). Involved in the regulation of epidermal differentiation and chondrocyte development.

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Products

Antibodies (14)

Proteins (2)

Type

Over-Expression Lysate (2)

Primary (14)

Target

KIF7 (16)

Reactivity

Human (14)

Mouse (3)

Rat (3)

Bovine (3)

Chimpanzee (3)

Monkey (3)

Orangutan (3)

Pig (3)

Application

IHC (2)

IHC-P (1)

WB (11)

ELISA (1)

IF (1)

IP (1)

Host

rabbit (11)

mouse (3)

Isotype

IgG (4)

IgG1 (1)

Clonality

monoclonal mc (3)

polyclonal pc (11)

Clone

3F8 (2)

3I4 (1)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (8)

Epitope

aa1224-1273 (4)

aa1266-1315 (4)

aa1225-1275 (1)

Publications

No (16)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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KIF7 Antibody (clone 3I4) LS-C767768

Antibody:

KIF7 Mouse anti-Human Monoclonal (3I4) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC-P

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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KIF7 Antibody LS-C754949

Antibody:

KIF7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$351

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KIF7 Antibody (clone 3F8) LS-C778345

Antibody:

KIF7 Mouse anti-Human Monoclonal (3F8) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

100 µg/$357

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KIF7 Antibody (clone 3F8) LS-C387353

Antibody:

KIF7 Mouse anti-Human Monoclonal (3F8) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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KIF7 Antibody (aa1225-1275) LS-C289428

Antibody:

KIF7 Rabbit anti-Human Polyclonal (aa1225-1275) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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KIF7 Antibody LS-C750549

Antibody:

KIF7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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KIF7 Antibody (aa1224-1273) LS-C146000

Antibody:

KIF7 Rabbit anti-Human Polyclonal (aa1224-1273) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

KIF7 Antibody (aa1224-1273, HRP) LS-C468826

Antibody:

KIF7 Rabbit anti-Human Polyclonal (aa1224-1273) (HRP) Antibody

Reactivity:

Bovine, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

KIF7 Antibody (aa1224-1273, Biotin) LS-C468824

Antibody:

KIF7 Rabbit anti-Human Polyclonal (aa1224-1273) (Biotin) Antibody

Reactivity:

Bovine, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

KIF7 Antibody (aa1224-1273, FITC) LS-C468825

Antibody:

KIF7 Rabbit anti-Human Polyclonal (aa1224-1273) (FITC) Antibody

Reactivity:

Bovine, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

KIF7 Antibody (aa1266-1315) LS-C187257

Antibody:

KIF7 Rabbit anti-Human Polyclonal (aa1266-1315) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

KIF7 Antibody (aa1266-1315, HRP) LS-C468849

Antibody:

KIF7 Rabbit anti-Human Polyclonal (aa1266-1315) (HRP) Antibody

Reactivity:

Pig, Orangutan, Human, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

KIF7 Antibody (aa1266-1315, Biotin) LS-C468827

Antibody:

KIF7 Rabbit anti-Human Polyclonal (aa1266-1315) (Biotin) Antibody

Reactivity:

Pig, Orangutan, Human, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

KIF7 Antibody (aa1266-1315, FITC) LS-C468848

Antibody:

KIF7 Rabbit anti-Human Polyclonal (aa1266-1315) (FITC) Antibody

Reactivity:

Pig, Orangutan, Human, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

KIF7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102568

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

94.8 kDa

Price:

100 µg/$710

Select

Human KIF7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G94496

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

94.8 kDa

Price:

20 µg/$215

Viewing 1-16 of 16 product results

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