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Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex.
Gene Name: | ankyrin repeat and LEM domain containing 2 |
Synonyms: | ANKLE2, KIAA0692, LEMD7, LEM domain containing 7, Lem4 |
Target Sequences: | AA293060 NP_055929.1 Q86XL3 |
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