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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KF1 / RNF103

ring finger protein 103

KF1 / RNF103 contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene.

Gene Name: ring finger protein 103
Synonyms: RNF103, HKF-1, ZFP-103, ZFP103, KF-1, KF1, Ring finger protein 103
Target Sequences: NM_005667 NP_005658.1 O00237

Filtered By: None
Target
KF1 / RNF103 (6)
Reactivity
Human (6)
Bat (1)
Dog (1)
Horse (1)
Monkey (1)
Application
WB (1)
ELISA (5)
Peptide-ELISA (1)
RNAi (1)
Host
rabbit (4)
mouse (1)
goat (1)
Isotype
IgG (4)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (5)
Clone
3E7 (1)
Format
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (3)
Epitope
aa673-685 (1)
Publications
No (6)
Showing 1-6 of 6 results

KF1 / RNF103 Antibody (clone 3E7) LS-C198501
Mouse Monoclonal [clone 3E7] (IgG2a,k) to Human KF1 / RNF103
Human
ELISA RNAi WB
Unconjugated
100µg  $355.00
Western Blot analysis of RNF103 expression in transfected 293T cell line by RNF103 monoclonal antibody (M01), clone 3E7.Lane 1: RNF103 transfected lysate(79.405 KDa).Lane 2: Non-transfected lysate.
Western blot analysis of RNF103 over-expressed 293 cell line, cotransfected with RNF103 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with RNF103 monoclonal antibody (M01), clone 3E7 . GAPDH ( 36.1 kDa ) used as specificity and loading control.
Western Blot analysis of RNF103 expression in transfected 293T cell line by RNF103 monoclonal antibody (M01), clone 3E7.Lane 1: RNF103 transfected lysate(79.405 KDa).Lane 2: Non-transfected lysate.
Western blot analysis of RNF103 over-expressed 293 cell line, cotransfected with RNF103 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with RNF103 monoclonal antibody (M01), clone 3E7 . GAPDH ( 36.1 kDa ) used as specificity and loading control.

KF1 / RNF103 Antibody LS-C376475
Rabbit Polyclonal (IgG) to Human KF1 / RNF103
Human
ELISA
Unconjugated
50µg  $285.00; 100µg  $385.00

KF1 / RNF103 Antibody (HRP) LS-C376477
Rabbit Polyclonal (IgG) to Human KF1 / RNF103
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

KF1 / RNF103 Antibody (Biotin) LS-C376478
Rabbit Polyclonal (IgG) to Human KF1 / RNF103
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

KF1 / RNF103 Antibody (FITC) LS-C376479
Rabbit Polyclonal (IgG) to Human KF1 / RNF103
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00

KF1 / RNF103 Antibody (aa673-685) LS-C55029
Goat Polyclonal to Human KF1 / RNF103
Dog, Horse, Bat, Human, Monkey
Peptide-ELISA
Unconjugated
100µg  $335.00
Showing 1-6 of 6 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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