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KDM4A / JHDM3A / JMJD2A

lysine (K)-specific demethylase 4A

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.Isoform 2: Crucial for muscle differentiation, promotes transcriptional activation of the Myog gene by directing the removal of repressive chromatin marks at its promoter. Lacks the N-terminal demethylase domain.

Gene Name: lysine (K)-specific demethylase 4A
Synonyms: KDM4A, JMJD2A, Jumonji domain containing 2A, JMJD2, Jumonji domain containing 2, KIAA0677, JHDM3A, Lysine-specific demethylase 4A
Target Sequences: NM_014663 NP_055478.2 O75164

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Products
Antibodies (42)
Primary (42)
KDM4A / JHDM3A / JMJD2A (42)
Human (42)
Mouse (20)
Rat (2)
IHC (15)
IHC-P (7)
WB (28)
Flo (1)
DB (8)
ELISA (16)
ICC (7)
IF (9)
IP (3)
rabbit (35)
mouse (6)
sheep (1)
Product Group
IHCPlus (1)
IgG (20)
IgG1 (4)
IgG2a (2)
monoclonal mc (6)
polyclonal pc (36)
3559D5a (1)
5H1 (2)
6E10G4 (1)
APC (1)
APC Conjugated (2)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (23)
aa141-310 (8)
pTyr547 (7)
aa320-460 (5)
aa350-400 (2)
aa1010-C-term (1)
aa527-559 (1)
No (42)
KDM4A / JHDM3A / JMJD2A Antibody - Anti-KDM4A / JMJD2A antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$440
KDM4A / JHDM3A / JMJD2A Antibody - JMJD2A Antibody in Immunohistochemistry (IHC)
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KDM4A / JHDM3A / JMJD2A Mouse anti-Human Monoclonal (5H1) Antibody
Human
ICC, IF, IHC, WB
Unconjugated
100 µl/$541
KDM4A / JHDM3A / JMJD2A Antibody - IHC of paraffin-embedded colon cancer tissues (left) and human larynx cancer tissues (right) using KDM4A mouse monoclonal antibody with DAB staining.
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KDM4A / JHDM3A / JMJD2A Mouse anti-Human Monoclonal (5H1) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$435
KDM4A / JHDM3A / JMJD2A Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded colon cancer tissues (left) and human larynx cancer tissues (right) with DAB staining using JMJD2A Monoclonal Antibody.
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KDM4A / JHDM3A / JMJD2A Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
KDM4A / JHDM3A / JMJD2A Antibody - JMJD2A Antibody - IHC of JMJD2A in paraffin embedded mouse pancreas.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (aa320-460) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
KDM4A / JHDM3A / JMJD2A Antibody - JMJD2A Antibody - IHC of JMJD2A in paraffin embedded mouse pancreas.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (aa320-460) (Biotin) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
KDM4A / JHDM3A / JMJD2A Antibody - JMJD2A Antibody - IHC of JMJD2A in paraffin embedded mouse pancreas.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (aa320-460) (DY650) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
KDM4A / JHDM3A / JMJD2A Antibody - JMJD2A Antibody - IHC of JMJD2A in paraffin embedded mouse pancreas.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (aa320-460) (DY488) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
KDM4A / JHDM3A / JMJD2A Antibody - JMJD2A Antibody - IHC of JMJD2A in paraffin embedded mouse pancreas.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (aa320-460) (DY550) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
KDM4A / JHDM3A / JMJD2A Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution of 1:100
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
KDM4A / JHDM3A / JMJD2A Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using KDM4A Polyclonal Antibody at dilution of 1:40.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KDM4A / JHDM3A / JMJD2A Antibody - Western blot of KDM4A / JHDM3A / JMJD2A antibody.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (aa141-310) Antibody
Mouse, Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
KDM4A / JHDM3A / JMJD2A Antibody - Immunohistochemistry of paraffin-embedded mouse lung tissue.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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KDM4A / JHDM3A / JMJD2A Mouse anti-Human Monoclonal (6E10G4) Antibody
Human
ELISA, Flo
Unconjugated
100 µl/$459
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
KDM4A / JHDM3A / JMJD2A Antibody - Detection of Human JMJD2A by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-JMJD2A used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (aa350-400) Antibody
Human
IHC, IP
Unconjugated
10 µg/$295; 100 µl/$514
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
KDM4A / JHDM3A / JMJD2A Antibody - Western blot analysis of immunized recombinant protein, using anti-JMJD2A monoclonal antibody.
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KDM4A / JHDM3A / JMJD2A Mouse anti-Human Monoclonal (3559D5a) Antibody
Human
DB, WB
Unconjugated
100 µg/$486
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (pTyr547) Antibody
Human
DB, ELISA
Unconjugated
200 µl/$734
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (pTyr547) (FITC) Antibody
Human
DB, ELISA
FITC Conjugated
200 µl/$952
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (pTyr547) (APC) Antibody
Human
DB, ELISA
APC Conjugated
200 µl/$952
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (pTyr547) (PE) Antibody
Human
DB, ELISA
PE Conjugated
200 µl/$952
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (aa1010-C-term) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
KDM4A / JHDM3A / JMJD2A Antibody - Detection of Human JMJD2A by Immunohistochemistry. Sample: FFPE section of human ovarian tumor. Antibody: Affinity purified rabbit anti-JMJD2A used at a dilution of 1:250.
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KDM4A / JHDM3A / JMJD2A Rabbit anti-Human Polyclonal (aa350-400) Antibody
Human
IHC
Unconjugated
2.5 µg/$295; 100 µl/$532
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KDM4A / JHDM3A / JMJD2A Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µg/$786
Viewing 1-25 of 42 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).