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KCNMB2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.

Gene Name: potassium large conductance calcium-activated channel, subfamily M, beta member 2
Family/Subfamily: Ion Channel , Potassium channel - calcium-activated
Synonyms: KCNMB2, BK beta 2, HKCNMB2, Hbeta2, Maxi K beta 2, HCG1646471, K(VCA)beta-2, MaxiK channel beta 2 subunit, SLO-BETA2, BK channel subunit beta-2, BKbeta2, HBETA3, Maxi K channel subunit beta-2, Slo-beta-2
Target Sequences: NM_005832 NP_005823.1 Q9Y691

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Proteins (5)
Over-Expression Lysate (4)
Recombinant (1)
KCNMB2 (5)
No (5)
GST (1)
Myc-DDK (Flag) (4)
Human (3)
293T Cells (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
KCNMB2 Protein - 12.5% SDS-PAGE of human KCNMB2 stained with Coomassie Blue
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Wheat Germ Extract
GST
51.59 kDa
2 µg/$439
KCNMB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
26.9 kDa
100 µg/$494
KCNMB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
26.9 kDa
20 µg/$150
KCNMB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.9 kDa
20 µg/$150
KCNMB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.9 kDa
100 µg/$494
Viewing 1-5 of 5 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).