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KCNK3 / OAT1

potassium channel, subfamily K, member 3

KCNK3 / OAT1 is a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.

Gene Name: potassium channel, subfamily K, member 3
Family/Subfamily: Ion Channel , Potassium channel - two pore
Synonyms: KCNK3, Cardiac potassium channel, CTBAK-1, K2p3.1, OAT1, TASK, Two pore K(+) channel KT3.1, TASK-1, TASK1, TBAK1, Two P domain potassium channel
Target Sequences: NM_002246 NP_002237.1 O14649

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Proteins (1)
Recombinant (1)
KCNK3 / OAT1 (1)
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10His, N-terminus + Myc, C-terminus (1)
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Purified (1)
KCNK3 / OAT1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
50.5 kDa
100 µg/$1,801; 20 µg/$1,247
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).