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KCNK16 / TALK-1 belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Gene Name: | potassium channel, subfamily K, member 16 |
Family/Subfamily: | Ion Channel , Potassium channel - two pore |
Synonyms: | KCNK16, K2p16.1, TALK-1, TALK1 |
Target Sequences: | NM_032115 NP_115491.1 Q96T55 |
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