KCNJ12 / Kir2.2

potassium inwardly-rectifying channel, subfamily J, member 12

Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

KCNJ12 / Kir2.2 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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KCNJ12 / Kir2.2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110824

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.8 kDa

Price:

100 µg/$494

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Human KCNJ12 / Kir2.2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74666

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.8 kDa

Price:

20 µg/$150

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Human KCNJ12 / Kir2.2 Protein (Recombinant GST) (Full Length) - LS-G29115

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

73.37 kDa

Price:

10 µg/$479; 25 µg/$670

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