KANK1

KN motif and ankyrin repeat domains 1

Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading; the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.

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Proteins (5)

Type

Over-Expression Lysate (4)

Recombinant (1)

Target

KANK1 (5)

Publications

No (5)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (3)

Source

293T Cells (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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KANK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105859

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

129.6 kDa

Price:

100 µg/$494

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KANK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113417

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

147.1 kDa

Price:

100 µg/$494

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Human KANK1 Protein (Recombinant GST, N-terminus) (aa701-800) - LS-G61936

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human KANK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77026

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

147.1 kDa

Price:

20 µg/$150

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Human KANK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77027

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

129.6 kDa

Price:

20 µg/$150

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