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Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
Gene Name: | jun dimerization protein 2 |
Synonyms: | JDP2, Jun dimerization protein 2, JUNDM2 |
Target Sequences: | Q8WYK2 Q8WYK2 |
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