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JUN / c-Jun

jun proto-oncogene

c-Jun is a component of the transcription factor activator protein 1 (AP-1) that binds to and activates transcription at TRE/AP-1 elements. Phosphorylation of c-Jun at Ser 63/73, resulting in activation and c-Jun dependent transcription, occurs in response to extra or intracellular signals, including UV irradiation, growth factors and transforming oncoproteins.

Gene Name: jun proto-oncogene
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: JUN, Activator protein 1, AP-1, C-Jun, Jun proto-oncogene, p39, Jun oncogene, Proto-oncogene c-Jun, AP1, Enhancer-binding protein AP1, G0s7, Transcription factor AP-1, v-jun
Target Sequences: NM_002228 NP_002219.1 P05412

Publications (3)

1
Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos. Liao G, Tao Q, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsieh JC, Wylie C, Heasman J, Kuan CY. Proceedings of the National Academy of Sciences of the United States of America. 2006 103:16313-8. (WB) [PubMed:17060633] [PMC:PMC1637579]
2
Clara cells protein, prolactin and transcription factors of protein NF-?B and c-Jun/AP-1 levels in rats inhaled to stainless steel welding dust and its soluble form. Halatek T, Stanislawska M, Swiercz R, Domeradzka-Gajda K, Kuras R, Wasowicz W. International Journal of Occupational Medicine and Environmental Health. 2018 October;31:613-632. [Full Text Article] [PubMed:30283154]
3
HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy. Michael F Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L Messina, Jurgen C Becker, Dirk Schadendorf, Edward Seto, Vernon K Sondak, John M Koomen, Yian A Chen, Eric K Lau, Lixin Wan, Jonathan D Licht, Keiran S M Smalley. Cancer research. 2019 June;79:2947-2961. [Full Text Article] [PubMed:30987999] [PMC:PMC6548652]

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1306CT545.208.117 (1)
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JUN / c-Jun Antibody - Anti-JUN antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Neuroscience
JUN / c-Jun Rabbit anti-Human Polyclonal (aa210-259) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, Peptide-ELISA, WB
Unconjugated
50 µl/$440
JUN / c-Jun Antibody - Immunohistochemical analysis of c-Jun (pS63) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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JUN / c-Jun Rabbit anti-Human Polyclonal (pSer63) Antibody
Rabbit, Mouse, Sheep, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
JUN / c-Jun Antibody - Anti-JUN mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY JUN.
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JUN / c-Jun Mouse anti-Human Monoclonal (OTI3G2) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
JUN / c-Jun Antibody - Immunohistochemical analysis of c-Jun staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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JUN / c-Jun Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
ChrIP, Flo, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
JUN / c-Jun Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-JUN mouse monoclonal antibody.
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JUN / c-Jun Mouse anti-Human Monoclonal (OTI2A9) Antibody
Mouse, Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
JUN / c-Jun Antibody - IHC of paraffin-embedded human intima cancer tissues using c-Jun mouse monoclonal antibody with DAB staining.
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JUN / c-Jun Mouse anti-Human Monoclonal (5B1) Antibody
Mouse, Human, Monkey
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$436
JUN / c-Jun Antibody - Western blot of c-Jun phosphorylation expression in UV treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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JUN / c-Jun Rabbit anti-Human Polyclonal (pThr239) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
JUN / c-Jun Antibody - Western blot of c-Jun phosphorylation expression in UV treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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JUN / c-Jun Rabbit anti-Human Polyclonal (pSer63) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
JUN / c-Jun Antibody - Western blot of Acetyl-AP-1 (K271) antibody
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JUN / c-Jun Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$289; 100 µl/$319; 200 µl/$389
JUN / c-Jun Antibody - Immunohistochemical analysis of c-Jun (pT239) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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JUN / c-Jun Rabbit anti-Human Polyclonal (pThr239) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
JUN / c-Jun Antibody - Western blot of AP-1 antibody
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JUN / c-Jun Rabbit anti-Human Polyclonal (180-260 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µl/$289; 100 µl/$319; 200 µl/$389
Select
JUN / c-Jun Rabbit anti-Human Monoclonal Antibody
Mouse, Rat, Human, Monkey
ChrIP, IF, IHC, IP, WB
Unconjugated
50 µl/$343
JUN / c-Jun ELISA Kit
Select
DNA Binding
12 x 8-Well Microstrips
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$744
JUN / c-Jun Antibody - IHC of paraffin-embedded Human breast tissue using anti-JUN mouse monoclonal antibody.
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JUN / c-Jun Mouse anti-Human Monoclonal (OTI2D11) Antibody
Mouse, Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
JUN / c-Jun Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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JUN / c-Jun Rabbit anti-Human Polyclonal (pSer63) Antibody
Human
DB, IHC, IHC-P, WB
Unconjugated
400 µl/$396
JUN / c-Jun Antibody - Anti-JUN antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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JUN / c-Jun Rabbit anti-Human Polyclonal (aa201-250) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Select
JUN / c-Jun Rabbit anti-Human Polyclonal Antibody
Xenopus, Chicken, Zebrafish, Pig, Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Human, Monkey
IF, IHC, WB
Unconjugated
50 µg/$489
JUN / c-Jun Antibody - Immunohistochemical analysis of c-Jun (pY170) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
JUN / c-Jun Rabbit anti-Human Polyclonal (pTyr170) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$315
JUN / c-Jun Antibody - c-Jun Antibody in Immunohistochemistry (IHC)
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JUN / c-Jun Mouse anti-Human Monoclonal (5B1) Antibody
Mouse, Human, Non-Human Primate
Flo, ICC, IF, IHC, WB
Unconjugated
100 µl/$504
JUN / c-Jun Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded human intima canncer tissues with DAB staining using AP-1 Monoclonal Antibody.
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JUN / c-Jun Mouse anti-Human Monoclonal Antibody
Human, Monkey
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$393
Select
JUN / c-Jun Rabbit anti-Human Polyclonal (pSer73) Antibody
Xenopus, Chicken, Zebrafish, Pig, Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Human, Monkey
IHC, WB
Unconjugated
50 µg/$489
JUN / c-Jun Antibody - Immunofluorescence analysis of MCF7 cells.
Select
JUN / c-Jun Rabbit anti-Human Polyclonal (pSer63) Antibody
IF, WB
Unconjugated
20 µl/$263; 50 µl/$316; 100 µl/$391; 200 µl/$499
JUN / c-Jun Antibody - c-Jun Antibody in Immunohistochemistry (IHC)
Select
JUN / c-Jun Mouse anti-Human Monoclonal (4H9) Antibody
Mouse, Human
ICC, IF, IHC, WB
Unconjugated
100 µl/$504
JUN / c-Jun Antibody - IHC of paraffin-embedded cervical cancer tissues using c-Jun mouse monoclonal antibody with DAB staining.
Select
JUN / c-Jun Mouse anti-Human Monoclonal (4H9) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$436
JUN / c-Jun Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-JUN mouse monoclonal antibody.  heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Select
JUN / c-Jun Mouse anti-Human Monoclonal (UMAB49) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, PMA, WB
Unconjugated
100 µl/$493
Viewing 1-25 of 382 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).