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Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory.
Gene Name: | junctophilin 4 |
Synonyms: | JPH4, JP-4, Junctophilin 4, JP4, JPHL1, Junctophilin-4, KIAA1831, Junctophilin-like 1 protein, Junctophilin like 1 |
Target Sequences: | NM_032452 NP_115828.2 Q96JJ6 |
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