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ITPKA

inositol-trisphosphate 3-kinase A

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-triphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-triphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.

Gene Name: inositol-trisphosphate 3-kinase A
Family/Subfamily: Non-protein Kinase , ITPK
Synonyms: ITPKA, IP3-3KA, IP3KA, InsP 3-kinase A, IP3 3-kinase A, IP3K A
Target Sequences: NM_002220 NP_002211.1 P23677

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
ITPKA (3)
No (3)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
ITPKA Protein - Purified recombinant protein ITPKA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
50.8 kDa
20 µg/$1,107
ITPKA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
50.8 kDa
100 µg/$494
ITPKA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
50.8 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).