ITGB3BP

Beta 3-endonexin (ITGB3BP)

Transcription coregulator that can have both coactivator and corepressor functions. Isoform 1, but not other isoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. In contrast, it does not coactivate nuclear receptors for retinoic acid, vitamin D, progesterone receptor, nor glucocorticoid. Acts as a coactivator for estrogen receptor alpha. Acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. Induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases. May also act as an inhibitor of cyclin A-associated kinase. Also acts a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.

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Products

Antibodies (24)

Type

Primary (24)

Target

ITGB3BP (24)

Reactivity

Human (24)

Mouse (4)

Rat (3)

Chimpanzee (3)

Monkey (3)

Application

IHC (6)

IHC-P (1)

WB (20)

ELISA (10)

IF (5)

Peptide-ELISA (1)

Host

rabbit (16)

mouse (8)

Isotype

IgG (11)

IgG1 (2)

IgG2a,k (6)

Clonality

monoclonal mc (8)

polyclonal pc (16)

Clone

OTI4H1 (2)

Format

APC Conjugated (1)

Biotin Conjugated (3)

Carrier-free (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (13)

Epitope

N-Terminus (4)

aa36-85 (4)

aa1-100 (1)

Publications

No (24)

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ITGB3BP Antibody (aa1-100) LS-C308545

Antibody:

ITGB3BP Mouse anti-Human Monoclonal (aa1-100) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$705

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ITGB3BP Antibody (HRP) LS-C542782

Antibody:

ITGB3BP Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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ITGB3BP Antibody (Biotin) LS-C522650

Antibody:

ITGB3BP Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

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ITGB3BP Antibody (FITC) LS-C532695

Antibody:

ITGB3BP Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

FITC Conjugated

Price:

100 µl/$904

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ITGB3BP Antibody (APC) LS-C514436

Antibody:

ITGB3BP Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

APC Conjugated

Price:

100 µl/$904

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ITGB3BP Antibody (PE) LS-C650895

Antibody:

ITGB3BP Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

PE Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

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ITGB3BP Antibody LS-C660208

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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ITGB3BP Antibody LS-C675916

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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ITGB3BP Antibody LS-C809144

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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ITGB3BP Antibody LS-C400825

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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ITGB3BP Antibody LS-C833373

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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ITGB3BP Antibody LS-C779080

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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ITGB3BP Antibody LS-C749838

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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ITGB3BP Antibody (clone OTI4H1) LS-C336859

Antibody:

ITGB3BP Mouse anti-Human Monoclonal (OTI4H1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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ITGB3BP Antibody (clone OTI4H1, Carrier-free) LS-C789899

Antibody:

ITGB3BP Mouse anti-Human Monoclonal (Carrier-free) (OTI4H1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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ITGB3BP Antibody (aa36-85) LS-C81978

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal (aa36-85) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ITGB3BP Antibody (aa36-85, HRP) LS-C459504

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody

Reactivity:

Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

ITGB3BP Antibody (aa36-85, Biotin) LS-C459501

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody

Reactivity:

Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

ITGB3BP Antibody (aa36-85, FITC) LS-C459502

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal (aa36-85) (FITC) Antibody

Reactivity:

Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ITGB3BP Antibody (N-Terminus) LS-C345520

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

ITGB3BP Antibody (N-Terminus, HRP) LS-C459506

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

ITGB3BP Antibody (N-Terminus, Biotin) LS-C459503

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

ITGB3BP Antibody (N-Terminus, FITC) LS-C459505

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ITGB3BP Antibody LS-C334331

Antibody:

ITGB3BP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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