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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Unfortunately, the antibody (ID:12400) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



ITGB3 / Integrin Beta 3 / CD61

integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Gene Name: integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3
Target Sequences: NM_000212 NP_000203.2 P05106

Publications (1)

1
Abnormal whole blood thrombi in humans with inherited platelet receptor defects. Castellino FJ, Liang Z, Davis PK, Balsara RD, Musunuru H, Donahue DL, Smith DL, Sandoval-Cooper MJ, Ploplis VA, Walsh M. PloS one. 2012 7:e52878. [PubMed:23300803] [PMC:PMC3532496] Related Antibodies: LS-C165324.

Filtered By: None
Target
itgb3-integrin-beta-3-cd61 (217)
Reactivity
Human (188)
Mouse (62)
Rat (43)
Bat (1)
Bovine (21)
Chicken (3)
Chimpanzee (3)
Dog (20)
Gibbon (3)
Guinea pig (1)
Horse (13)
Monkey (11)
Non-Human Primates (2)
Pig (17)
Rabbit (8)
Sheep (8)
Xenopus (2)
Zebrafish (2)
Application
IHC (102)
IHC-Fr (21)
IHC-P (39)
WB (117)
Flo (97)
ELISA (20)
FLISA (1)
Func (2)
ICC (25)
IF (5)
IP (47)
Peptide-ELISA (4)
Host
rabbit (88)
mouse (109)
hamster (19)
rat (1)
Isotype
IgG (68)
IgG1 (74)
IgG1,k (15)
IgG2a,k (1)
IgM (15)
IgM,k (2)
Clonality
monoclonal mc (129)
polyclonal pc (88)
Clone
1-55-4 (1)
25E11 (2)
2C9.G3 (4)
2f2 (2)
43.PL (2)
ABT-CD61 (1)
BB10 (2)
BL-E6 (1)
BV4 (2)
CRC54 (2)
HM beta 3.1 (1)
JM2E5 (4)
PM6/13 (5)
VIPL2 (2)
VI-PL2 (3)
Y2/51 (5)
Format
AP Conjugated (15)
APC (2)
APC Conjugated (12)
Azide-free (4)
Biotin Conjugated (20)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (34)
HRP Conjugated (17)
PE Conjugated (25)
PerCP Conjugated (1)
Ready-to-Use (1)
RPE Conjugated (2)
Unconjugated (87)
Epitope
aa135-377 (18)
N-Terminus (9)
aa734-760 (8)
pTyr773 (8)
Internal (7)
pTyr785 (7)
C-Terminus (4)
aa58-107 (4)
Ser778 (1)
Thr767 (1)
aa609-788 (1)
aa621-670 (1)
aa710-790 (1)
aa720-800 (1)
aa731-780 (1)
aa739-788 (1)
aa752-770 (1)
aa783-787 (1)
Publications
No (216)
Yes (1)
Showing 1-25 of 217 results

ITGB3 / Integrin Beta 3 / CD61 Antibody (N-Terminus) IHC-plus™ LS-A9416
Rabbit Polyclonal to Human ITGB3 / Integrin Beta 3 / CD61
Human
IHC IHC-P
Unconjugated
50µg 100µl 0.5mg/ml  $425.00
Anti-CD61 antibody LS-A9416 IHC of human placenta, terminal villi, red blood cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-CD61 antibody LS-A9416 IHC of human placenta, terminal villi, red blood cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone VI-PL2) IHC-plus™ LS-B4046
Mouse Monoclonal [clone VI-PL2] (IgG1,k) to Human ITGB3 / Integrin Beta 3 / CD61
Human
Flo IHC IHC-Fr IHC-P WB
Unconjugated
100µg 0.5mg/ml  $425.00
Anti-Integrin Beta 3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4046 concentration 20 ug/ml.
Anti-Integrin Beta 3 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4046 concentration 20 ug/ml.
Anti-Integrin Beta 3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4046 concentration 20 ug/ml.
Anti-Integrin Beta 3 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4046 concentration 20 ug/ml.

ITGB3 / Integrin Beta 3 / CD61 Antibody (FITC) LS-C44643
Hamster Monoclonal (IgG) to Mouse ITGB3 / Integrin Beta 3 / CD61
Mouse, Rat
Flo IP
FITC Conjugated
100µg 0.1mg/ml  $255.00

ITGB3 / Integrin Beta 3 / CD61 Antibody (RPE) LS-C44646
Hamster Monoclonal (IgG) to Mouse ITGB3 / Integrin Beta 3 / CD61
Mouse, Rat
Flo IP
RPE Conjugated
100tst  $265.00

ITGB3 / Integrin Beta 3 / CD61 Antibody (aa734-760) LS-C165324
Publications (1)
Publications (1)
Rabbit Polyclonal to Human ITGB3 / Integrin Beta 3 / CD61
Human
Flo IHC IHC-P WB
Unconjugated
400µl  $305.00
Formalin-fixed and paraffin-embedded human testis tissue reacted with ITGB3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of ITGB3 Antibody in CEM cell line lysates (35 ug/lane). ITGB3 (arrow) was detected using the purified antibody.(2 ug/ml)
Formalin-fixed and paraffin-embedded human testis tissue reacted with ITGB3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of ITGB3 Antibody in CEM cell line lysates (35 ug/lane). ITGB3 (arrow) was detected using the purified antibody.(2 ug/ml)

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone JM2E5) LS-C122000
Mouse Monoclonal [clone JM2E5] (IgG1) to Pig ITGB3 / Integrin Beta 3 / CD61
Dog, Bovine, Pig, Horse, Human
Flo IHC IHC-Fr IHC-P IP WB
Unconjugated
100µg 1mg/ml  $485.00

ITGB3 / Integrin Beta 3 / CD61 Antibody LS-C13870
Mouse Monoclonal (IgG1) to Human ITGB3 / Integrin Beta 3 / CD61
Human
Flo Func WB
Unconjugated
100µg 1mg/ml  $665.00

ITGB3 / Integrin Beta 3 / CD61 Antibody (Internal) IHC-plus™ LS-A9418
Rabbit Polyclonal to Human ITGB3 / Integrin Beta 3 / CD61
Human
IHC IHC-P
Unconjugated
50µg 0.9mg/ml  $425.00
Anti-CD61 antibody LS-A9418 IHC of human placenta, terminal villi, red blood cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CD61 antibody LS-A9418 IHC of human placenta, terminal villi, red blood cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone 2f2) LS-C311998
Mouse Monoclonal [clone 2f2] (IgG1,k) to Human ITGB3 / Integrin Beta 3 / CD61
Human
IHC IHC-Fr IHC-P
Unconjugated
100µl  $235.00; 500µl  $325.00
IHC of CD61 on FFPE Bone Marrow tissue.
IHC of CD61 on FFPE Bone Marrow tissue.

ITGB3 / Integrin Beta 3 / CD61 Antibody (aa752-770) LS-C312789
Rabbit Polyclonal to Human ITGB3 / Integrin Beta 3 / CD61
Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $355.00
ITGB3 / Integrin Beta 3 / CD61 antibody. IHC(P): Human Breast Cancer Tissue.
WB of ITGB3 / Integrin Beta 3 / CD61 antibody. All lanes: Anti-ITGB3 at 0.5ug/ml. Lane 1: JURKAT Whole Cell Lysate at 40ug. Lane 2: RAJI Whole Cell Lysate at 40ug. Lane 3: CEM Whole Cell Lysate at 40ug. Lane 4: COLO320 Whole Cell Lysate at 40ug. Predicted bind size: 87KD. Observed bind size: 87KD.
ITGB3 / Integrin Beta 3 / CD61 antibody. IHC(P): Human Breast Cancer Tissue.
WB of ITGB3 / Integrin Beta 3 / CD61 antibody. All lanes: Anti-ITGB3 at 0.5ug/ml. Lane 1: JURKAT Whole Cell Lysate at 40ug. Lane 2: RAJI Whole Cell Lysate at 40ug. Lane 3: CEM Whole Cell Lysate at 40ug. Lane 4: COLO320 Whole Cell Lysate at 40ug. Predicted bind size: 87KD. Observed bind size: 87KD.

ITGB3 / Integrin Beta 3 / CD61 Antibody (C-Terminus) LS-C352409
Rabbit Polyclonal to Human ITGB3 / Integrin Beta 3 / CD61
Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Pig, Human, Monkey
ICC IF IHC IHC-P IP WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of CD61 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of CD61 staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Immunohistochemical analysis of CD61 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of CD61 staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone JM2E5, FITC) LS-C130089
Mouse Monoclonal [clone JM2E5] (IgG1) to Pig ITGB3 / Integrin Beta 3 / CD61
Dog, Bovine, Pig, Horse, Human
Flo
FITC Conjugated
100µg 0.1mg/ml  $905.00

ITGB3 / Integrin Beta 3 / CD61 Antibody LS-C13859
Mouse Monoclonal (IgG1) to Human ITGB3 / Integrin Beta 3 / CD61
Human
Flo IHC IHC-Fr IHC-P IP WB
Unconjugated
100µg 0.1mg/ml  $385.00

ITGB3 / Integrin Beta 3 / CD61 Antibody (FITC) LS-C43903
Mouse Monoclonal (IgG1) to Rat ITGB3 / Integrin Beta 3 / CD61
Rat
Flo IHC IHC-Fr IP
FITC Conjugated
100tst 0.1mg/ml  $305.00

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone Y2/51) IHC-plus™ LS-B15763
Mouse Monoclonal [clone Y2/51] (IgG1) to Human ITGB3 / Integrin Beta 3 / CD61
Human
Flo IHC-Fr IHC-P WB
Unconjugated
50µg  $425.00
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone JM2E5) LS-C187486
Mouse Monoclonal [clone JM2E5] (IgG1) to Pig ITGB3 / Integrin Beta 3 / CD61
Dog, Bovine, Pig, Horse, Human
Flo IHC IHC-Fr IHC-P IP WB
Unconjugated
100µg 1mg/ml  $325.00

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone JM2E5, FITC) LS-C188255
Mouse Monoclonal [clone JM2E5] (IgG1) to Pig ITGB3 / Integrin Beta 3 / CD61
Dog, Bovine, Pig, Horse, Human
Flo IHC IHC-Fr IHC-P IP WB
FITC Conjugated
100µg 0.1mg/ml  $620.00
Flow cytometry of porcine peripheral blood platelets with Mouse anti-Porcine CD61:FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of porcine peripheral blood platelets with Mouse anti-Porcine CD61:FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone 2C9.G3) LS-C106954
Hamster Monoclonal [clone 2C9.G3] (IgG) to Mouse ITGB3 / Integrin Beta 3 / CD61
Mouse
Flo IHC IHC-Fr
Unconjugated
50µg 0.5mg/ml  $215.00; 100µg  $245.00; 500µg  $325.00
Staining of C57Bl/6 bone marrow cells with 0.25 ug FG Purified Armenian hamster IgG isotype control (open histogram) or 0.25 ug Purified anti-mouse/rat CD61 (2C9. G3) (colored histogram) followed by biotin anti-Armenian hamster IgG and SAv-PE. Cells in the large scatter population were used for analysis.
Staining of C57Bl/6 bone marrow cells with 0.25 ug FG Purified Armenian hamster IgG isotype control (open histogram) or 0.25 ug Purified anti-mouse/rat CD61 (2C9. G3) (colored histogram) followed by biotin anti-Armenian hamster IgG and SAv-PE. Cells in the large scatter population were used for analysis.

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone 1-55-4) LS-C179832
Rat Monoclonal [clone 1-55-4] (IgG2a,k)
Mouse
Flo IP WB
Unconjugated
100µg 1mg/ml  $345.00
Immunoprecipitation Image
Immunoprecipitation Image

ITGB3 / Integrin Beta 3 / CD61 Antibody (aa739-788) IHC-plus™ LS-B12431
Rabbit Polyclonal (IgG) to Human ITGB3 / Integrin Beta 3 / CD61
Mouse, Rat, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
100µl 1mg/ml  $505.00
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of lysates from NIH/3T3 and A549 cells, using Integrin beta3 Antibody. The lane on the right is blocked with the synthesized peptide.
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of lysates from NIH/3T3 and A549 cells, using Integrin beta3 Antibody. The lane on the right is blocked with the synthesized peptide.

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone CRC54) LS-C202075
Mouse Monoclonal [clone CRC54] (IgG1,k) to Human ITGB3 / Integrin Beta 3 / CD61
Human
Flo IF IHC IHC-Fr WB
Unconjugated
1ml  $385.00

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone CRC54) LS-C123080
Mouse Monoclonal [clone CRC54] (IgG1,k) to Human ITGB3 / Integrin Beta 3 / CD61
Human
Flo IF IHC IHC-Fr
Unconjugated
1000µl  $575.00

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone 2C9.G3, FITC) LS-C106035
Hamster Monoclonal [clone 2C9.G3] (IgG) to Mouse ITGB3 / Integrin Beta 3 / CD61
Mouse
Flo
FITC Conjugated
50µg  $225.00; 100µg 0.5mg/ml  $275.00; 500µg  $375.00
Staining of C57Bl/6 bone marrow cells with 0.5 ug FITC Armenian hamster IgG isotype control (open histogram) or 0.5 ug FITC anti-mouse/rat CD61 (2C9. G3) (colored histogram). Cells in the lymphoid gates were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of C57Bl/6 bone marrow cells with myeloid gates were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of C57Bl/6 bone marrow cells with 0.5 ug FITC Armenian hamster IgG isotype control (open histogram) or 0.5 ug FITC anti-mouse/rat CD61 (2C9. G3) (colored histogram). Cells in the lymphoid gates were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of C57Bl/6 bone marrow cells with myeloid gates were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

ITGB3 / Integrin Beta 3 / CD61 Antibody LS-C78665
Mouse Monoclonal (IgG1) to Human ITGB3 / Integrin Beta 3 / CD61
Human
Flo IHC IHC-P WB
Unconjugated
200µg  $590.00

ITGB3 / Integrin Beta 3 / CD61 Antibody (clone PM6/13) LS-C351636
Mouse Monoclonal [clone PM6/13] (IgG1) to Human ITGB3 / Integrin Beta 3 / CD61
Human
Flo IHC IHC-Fr IHC-P IP WB
Unconjugated
100µg 0.1mg/ml  $265.00
Showing 1-25 of 217 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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