ITGA8 / Integrin Alpha 8

integrin, alpha 8

Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ITGA8 / Integrin Alpha 8 (5)

Publications

No (5)

Tag

GST, N-terminus (1)

His-GST-S (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human ITGA8 / Integrin Alpha 8 Protein (Recombinant GST, N-terminus) (aa836-935) - LS-G60756

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ITGA8 / Integrin Alpha 8 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66041

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

117.3 kDa

Price:

20 µg/$1,107

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ITGA8 / Integrin Alpha 8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117188

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

117.3 kDa

Price:

100 µg/$710

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Human ITGA8 / Integrin Alpha 8 Protein (Recombinant His-GST-S) (aa907-1063) - LS-G24637

Source:

E. coli

Tag:

His-GST-S

Molecular Weight:

47.6 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Human ITGA8 / Integrin Alpha 8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76808

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

117.3 kDa

Price:

20 µg/$215

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