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ISG54 / IFIT2

interferon-induced protein with tetratricopeptide repeats 2

IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.

Gene Name: interferon-induced protein with tetratricopeptide repeats 2
Synonyms: IFIT2, Cig42, GARG-39, IFI-54, IFI-54K, IFIT-2, ISG-54 K, IFI54, p54, Interferon-induced protein 54, ISG-54K, ISG54, G10P2
Target Sequences: M14660 AAA59191.1 P09913

☰ Filters
Products
Antibodies (30)
Primary (30)
ISG54 / IFIT2 (30)
Human (30)
Mouse (1)
Rat (1)
Chimpanzee (3)
Gibbon (3)
Monkey (3)
Orangutan (3)
IHC (4)
IHC-P (2)
WB (26)
ELISA (13)
IF (3)
Peptide-ELISA (1)
rabbit (29)
mouse (1)
IgG (26)
polyclonal pc (30)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (14)
aa307-335 (7)
N-Terminus (4)
aa100-321 (1)
aa320-370 (1)
No (30)
ISG54 / IFIT2 Antibody
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa100-321) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
Select
ISG54 / IFIT2 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
ISG54 / IFIT2 Antibody - Western blot analysis IFIT2 using HeLa whole cells lysates
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ISG54 / IFIT2 Antibody - Immunohistochemistry Dilution at 1:600 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ISG54 / IFIT2 Antibody - IFIT2 antibody Western blot of Fetal Liver lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ISG54 / IFIT2 Antibody - Western Blot: IFIT2 Antibody - Analysis of IFIT2 in human K562 lysate in the 1) absence and 2) presence of immunizing peptide, and 3) mouse RAW lysate probed with 4 ug/ml of IFIT2 antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa320-370) Antibody
Mouse, Human
WB
Unconjugated
0.1 mg/$386
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
ISG54 / IFIT2 Antibody - IFIT2 Antibody western blot of 293 cell line lysates (35 ug/lane). The IFIT2 antibody detected the IFIT2 protein (arrow).
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) Antibody
Human
WB
Unconjugated
400 µl/$393
ISG54 / IFIT2 Antibody - Western blot analysis of extracts of various cell lines, using IFIT2 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ISG54 / IFIT2 Antibody - Western blot analysis of extracts of various cell lines using IFIT2 Polyclonal Antibody at dilution of 1:3000.
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ISG54 / IFIT2 Antibody - Immunochemical staining of human IFIT2 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Select
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
Viewing 1-25 of 30 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).