IRF4

interferon regulatory factor 4

Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

IRF4 (8)

Publications

No (8)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

GST, N-terminus + His, C-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human IRF4 Protein (Recombinant 6His, N-terminus) (Asn2-Glu451) - LS-G26517

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

54 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human IRF4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66069

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.6 kDa

Price:

20 µg/$1,107

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Human IRF4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76848

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.6 kDa

Price:

20 µg/$150

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IRF4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117958

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.6 kDa

Price:

100 µg/$494

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Human IRF4 Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G144897

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

79.6 kDa

Price:

50 µg/$419

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Human IRF4 Protein (Recombinant GST) (Full Length) - LS-G29082

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

75.35 kDa

Price:

2 µg/$439

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Human IRF4 Protein (Recombinant GST, N-terminus) (aa342-451) - LS-G59013

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse IRF4 Protein (Recombinant His-T7) (aa175-433) - LS-G14242

Source:

E. coli

Tag:

His-T7

Molecular Weight:

33.6 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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