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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IPO13 / LGL2

importin 13

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the loading of import substrates onto IPO13.

Gene Name: importin 13
Synonyms: IPO13, IMP13, Importin-13, Karyopherin 13, Late gestation lung 2, KIAA0724, Ran binding protein 13, Ran-binding protein 13, Importin 13, KAP13, Karyopherin-13, LGL2, RANBP13
Target Sequences: NM_014652 NP_055467.3 O94829

Filtered By: None
Target
IPO13 / LGL2 (9)
Reactivity
Human (8)
Mouse (2)
Rat (2)
Bovine (1)
Application
IHC (5)
IHC-P (1)
WB (4)
ELISA (8)
ICC (1)
IF (1)
IP (1)
Host
rabbit (9)
Isotype
IgG (7)
Clonality
polyclonal pc (9)
Format
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (6)
Epitope
aa222-420 (1)
aa901-963 (1)
Publications
No (9)
Showing 1-9 of 9 results

IPO13 / LGL2 Antibody (aa901-963) LS-C185927
Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Mouse, Bovine, Rat, Human
ICC IHC IHC-P IP WB
Unconjugated
100µl 1mg/ml  $335.00
IHC of paraffin-embedded CL1-5 xenograft using Importin 13 antibody at 1:100 dilution.
Immunofluorescence of paraformaldehyde-fixed HeLa using Importin 13 antibody at 1:200 dilution.
IHC of paraffin-embedded CL1-5 xenograft using Importin 13 antibody at 1:100 dilution.
Immunofluorescence of paraformaldehyde-fixed HeLa using Importin 13 antibody at 1:200 dilution.

IPO13 / LGL2 Antibody LS-C666476
Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Human
ELISA IF IHC WB
Unconjugated
100µg  $335.00

IPO13 / LGL2 Antibody LS-C152637
Rabbit Polyclonal to Human IPO13 / LGL2
ELISA IHC WB
Unconjugated
100µg  $335.00

IPO13 / LGL2 Antibody (aa222-420) LS-C178635
Rabbit Polyclonal to Human IPO13 / LGL2
Human
ELISA IHC WB
Unconjugated
100µg 1mg/ml  $255.00
Immunohistochemistry Image
Western blot Image
Immunohistochemistry Image
Western blot Image

IPO13 / LGL2 Antibody LS-C405082
Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human colon cancer using IPO13 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human colon cancer using IPO13 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human colon cancer using IPO13 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human colon cancer using IPO13 Polyclonal Antibody at dilution of 1:25.

IPO13 / LGL2 Antibody LS-C395903
Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Human
ELISA
Unconjugated
50µg  $285.00; 100µg  $385.00

IPO13 / LGL2 Antibody (HRP) LS-C395902
Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

IPO13 / LGL2 Antibody (Biotin) LS-C395884
Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

IPO13 / LGL2 Antibody (FITC) LS-C395931
Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00
Showing 1-9 of 9 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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