IPAF / NLRC4

NLR family, CARD domain containing 4

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and proteases including several members of the caspase family. Another family of proteins that functions as a critical regulator of apoptosis and NF-kB signaling pathways is the CED-4/Apaf-1 (apoptosis protein activating factor-1) protein family. Ipaf (ICE protease activating factor) is a CED-4/Apaf-1 family member that activates caspase-1/ICE and can induce apoptosis in human cells in a caspase-1 dependent manner. Ipaf and caspase-1 are thought to interact with each other through the association of the Ipaf amino-terminal CARD (caspase recruitment domain) and amino-terminal CARD of caspase-1.

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Products

Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

IPAF / NLRC4 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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IPAF / NLRC4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110699

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

116 kDa

Price:

100 µg/$494

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Human IPAF / NLRC4 Protein (Recombinant GST, N-terminus) (aa531-630) - LS-G63012

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human IPAF / NLRC4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85035

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

116 kDa

Price:

20 µg/$150

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