IL7

interleukin 7

IL7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

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Products

Proteins (36)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (3)

Recombinant (32)

Target

IL7 (36)

Format

Animal-free (1)

Publications

No (36)

Tag

6His, C-terminus (6)

6His-SUMO, N-terminus (1)

8His, C-terminus (1)

GST (1)

His (2)

His, C-Terminal (2)

His, N-Terminal (3)

His,C-terminus (1)

His-T7 (1)

Human Mutant IgG1 Fc (1)

Myc-DDK (Flag) (2)

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Species

Human (23)

Mouse (10)

Rat (2)

Source

293T Cells (1)

CHO Cells (3)

E. coli (17)

HEK 293 Cells (5)

Human Cells (2)

Insect Cells (1)

Mammalian Cells (4)

Wheat Germ Extract (1)

Purification

Purified (13)

Low Endotoxin Level

Low endotoxin level (22)

Biologically Active

Biologically active (17)

Animal-free

Animal-free (1)

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Human IL7 Protein (Recombinant Human Mutant IgG1 Fc) (aa26-177) - LS-G4075

Source:

CHO Cells

Tag:

Human Mutant IgG1 Fc

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

50 µg/$519

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Human IL7 Protein (Recombinant 6His, C-terminus) (Asp26-His177) - LS-G39480

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

18.4kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353

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IL7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122942

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.19 kDa

Price:

100 µg/$494

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Human IL7 Protein (Over-Expression Cell Culture Supernatant His, N-Terminal) (Asp26-His177) - LS-G136079

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~17 kDa

Price:

200 µl/$283

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Human IL7 Protein (Over-Expression Lysate His, N-Terminal) (Asp26-His177) - LS-G136082

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~17 kDa

Price:

100 µg/$298

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Human IL7 Protein (Recombinant 8His, C-terminus) - LS-G137670

Source:

HEK 293 Cells

Tag:

8His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 152 amino acid recombinant protein has a predicted molecular mass of approximately 18.8 kD. The DTT-reduced and non-reduced protein migrate at approximately 20- 30 kD by SDS-PAGE. The C-terminal contains an 8His-(TG8HGGQ)-tag.

Price:

10 µg/$352; 25 µg/$459; 100 µg/$1,065; 500 µg/$2,285

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Human IL7 Protein (Recombinant) - LS-G145678

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

17.4 kDa

Price:

10 µg/$364; 1 mg/$4,545

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Human IL7 Protein (Recombinant GST) (Full Length) - LS-G29036

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

42.46 kDa

Price:

10 µg/$479; 25 µg/$670

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Rat IL7 Protein (Recombinant His) (aa26-159) - LS-G24077

Source:

E. coli

Tag:

His

Molecular Weight:

19.4 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Mouse IL7 Protein (Recombinant) - LS-G37814

Tag:

None

Molecular Weight:

15 kDa

Price:

10 µg/$460

Select

Human IL7 Protein (Recombinant) - LS-G37684

Tag:

None

Molecular Weight:

17.4KD

Price:

10 µg/$484

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Human IL7 Protein (Recombinant 6His-SUMO, N-terminus) (aa26-177) - LS-G56010

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

100 µg/$1,128; 20 µg/$721

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Human IL7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76926

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.19 kDa

Price:

20 µg/$150

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Mouse IL7 Protein (Recombinant) (aa26-154) - LS-G5874

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

14.9 kDa

Price:

10 µg/$388; 100 µg/$1,466; 500 µg/$3,025

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Human IL7 Protein (Recombinant) (aa26-177) - LS-G5718

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

17.4 kDa

Price:

10 µg/$388; 100 µg/$1,466; 500 µg/$3,025

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Mouse IL7 Protein (Recombinant) - LS-G206

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

15.0 kDa

Price:

2 µg/$262; 10 µg/$335

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Rat IL7 Protein (Recombinant) - LS-G397

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

15.0 kDa

Price:

2 µg/$268; 10 µg/$349

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Human IL7 Protein (Recombinant) - LS-G158

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

17.4 kDa

Price:

2 µg/$268; 10 µg/$349

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Human IL7 Protein (Recombinant) - LS-G3660

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

2 µg/$281; 10 µg/$369

• Unmodified
• Animal-free

• Unmodified
• Animal-free

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Mouse IL7 Protein (Recombinant) - LS-G131562

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

10 µg/$395

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Mouse IL7 Protein (Recombinant 6His, C-terminus) (Full Length) - LS-G136720

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

15.9 kDa

Price:

50 µg/$698; 10 µg/$356; 1 mg/$3,095; 500 µg/$1,987

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Human IL7 Protein (Recombinant) (Full Length) - LS-G137400

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

17.5 kDa

Price:

50 µg/$698; 10 µg/$356; 1 mg/$3,932; 500 µg/$2,459

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Human IL7 Protein (Recombinant 6His, C-terminus) (Full Length) - LS-G137404

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

18.4 kDa

Price:

50 µg/$698; 10 µg/$356; 1 mg/$3,095; 500 µg/$2,167

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Mouse IL7 Protein (Recombinant) - LS-G137669

Source:

Insect Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 148 amino acid recombinant protein (with ADL-His9-SSGIEGR at N-terminus) has a predicted molecular mass of approximately 17 kD. The DTT-reduced and non-reduced protein migrates at approximately 20 kD by SDS-PAGE.

Price:

10 µg/$352; 25 µg/$459

Select

Human IL7 Protein (Recombinant His,C-terminus) - LS-G134267

Source:

HEK 293 Cells

Tag:

His,C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

~27 kDa (SDS-PAGE)

Price:

10 µg/$358; 50 µg/$690

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