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Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
IL5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
| Gene Name: | interleukin 5 (colony-stimulating factor, eosinophil) |
| Family/Subfamily: | Hormone , not assigned-Hormone |
| Synonyms: | IL5, EDF, Interleukin-5, IL-5, T-cell replacing factor, TRF |
| Target Sequences: | NM_000879 NP_000870.1 P05113 |
Publications (1)
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