IL4R / CD124

interleukin 4 receptor

IL4R / CD124 is the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

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Products

Proteins (22)

Type

Over-Expression Lysate (2)

Recombinant (20)

Target

IL4R / CD124 (22)

Publications

No (22)

Tag

6His, C-terminus (4)

6His, N-terminus (1)

6His-SUMOstar, N-terminus (1)

Fc, C-terminus (6)

GST, N-terminus (1)

His (3)

His,C-terminus (1)

His-T7 (1)

mFc, C-terminus (1)

Myc-DDK (Flag) (2)

Species

Crab-eating macaque (1)

Cynomolgus (1)

Human (11)

Mouse (3)

Pig (2)

Rat (3)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (3)

Human (2)

Human Cells (4)

Mammalian Cells (7)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (7)

Low Endotoxin Level

Low endotoxin level (15)

Biologically Active

Biologically active (3)

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Human IL4R / CD124 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76916

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

89.66 kDa

Price:

20 µg/$215

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IL4R / CD124 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123205

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

89.66 kDa

Price:

100 µg/$710

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Pig IL4R / CD124 Protein (Recombinant 6His-SUMOstar, N-terminus) - LS-G136674

Source:

Yeast

Tag:

6His-SUMOstar, N-terminus

Molecular Weight:

40.2 kDa

Price:

100 µg/$570; 20 µg/$395; 1 mg/$1,973

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Rat IL4R / CD124 Protein (Recombinant Fc, C-terminus) (Met1-Arg232) - LS-G138524

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

50.9 kDa

Price:

50 µg/$532

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Mouse IL4R / CD124 Protein (Recombinant 6His, C-terminus) - LS-G146283

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.2 kDa

Price:

10 µg/$265; 50 µg/$373

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Cynomolgus IL4R / CD124 Protein (Recombinant Fc, C-terminus) - LS-G146309

Source:

Human

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

50.7 kDa

Price:

10 µg/$327; 50 µg/$574

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Mouse IL4R / CD124 Protein (Recombinant Fc, C-terminus) (Ile26-Arg233) - LS-G139396

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

51.5 kDa

Price:

10 µg/$277; 50 µg/$389

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Mouse IL4R / CD124 Protein (Recombinant His-T7) (aa26-233) - LS-G24610

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.1 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human IL4R / CD124 Protein (Recombinant) - LS-G27210

Source:

HEK 293 Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

40-45 kDa (SDS-PAGE)

Price:

50 µg/$615; 10 µg/$304; 1 mg/$4,795

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Human IL4R / CD124 Protein (Recombinant GST, N-terminus) (aa26-135) - LS-G58973

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Pig IL4R / CD124 Protein (Recombinant 6His, N-terminus) (aa33-240) - LS-G56806

Source:

E. coli

Tag:

6His, N-terminus

Price:

100 µg/$500; 20 µg/$364; 1 mg/$1,679

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Human IL4R / CD124 Protein (Recombinant His) (Met1-His232) - LS-G98604

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.3 kDa

Price:

100 µg/$843

Select

Rat IL4R / CD124 Protein (Recombinant His) (Met1-Arg232) - LS-G98424

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.3 kDa

Price:

50 µg/$532

Select

Human IL4R / CD124 Protein (Recombinant 6His, C-terminus) - LS-G137382

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

24.4 kDa

Price:

50 µg/$516; 10 µg/$313; 1 mg/$2,321; 500 µg/$1,666

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Human IL4R / CD124 Protein (Recombinant Fc, C-terminus) - LS-G137386

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

50.2 kDa

Price:

50 µg/$453; 10 µg/$303; 1 mg/$2,837; 500 µg/$1,987

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Crab-eating macaque IL4R / CD124 Protein (Recombinant His,C-terminus) (Met26-Arg232) - LS-G139906

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

24.6 kDa

Price:

10 µg/$288; 50 µg/$436

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Human IL4R / CD124 Protein (Recombinant Fc, C-terminus) (Met26-Gln231) - LS-G139105

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

50.2 kDa

Price:

10 µg/$281; 50 µg/$389

Select

Human IL4R / CD124 Protein (Recombinant 6His, C-terminus) (Met26-His232) - LS-G139621

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

24.4 kDa

Price:

10 µg/$288; 50 µg/$436

Select

Human IL4R / CD124 Protein (Recombinant mFc, C-terminus) (Met26-Gln231) - LS-G139805

Source:

Mammalian Cells

Tag:

mFc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

50.2 kDa

Price:

10 µg/$288; 50 µg/$436

Select

Human IL4R / CD124 Protein (Recombinant 6His, C-terminus) (Met26-His232) - LS-G40357

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

24.4kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,377; 1 mg/$1,765

Select

Human IL4R / CD124 Protein (Recombinant Fc, C-terminus) (Met26-Gln231) - LS-G40362

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

50.2kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

Select

Rat IL4R / CD124 Protein (Recombinant His) (aa26-232) - LS-G14641

Source:

E. coli

Tag:

His

Molecular Weight:

25.1 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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