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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL36RN / IL1F5

interleukin 36 receptor antagonist

Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Gene Name: interleukin 36 receptor antagonist
Family/Subfamily: IL-1 , not assigned-IL-1
Synonyms: IL36RN, FIL1, FIL1D, IL-1 delta, IL-1 related protein 3, IL-1HY1, IL-1RP3, IL-1-related protein 3, IL1F5, IL1RP3, IL1L1, IL36RA, Interleukin-1 delta, Family of interleukin 1-delta, FIL1 delta, IL-1L1, IL-1ra homolog 1, Interleukin-1 family member 5, Interleukin-1-like protein 1, FIL1(DELTA), IL-1F5, IL1HY1, Interleukin-1 HY1, PSORP
Target Sequences: NM_012275 NP_036407.1 Q9UBH0

Filtered by: None
Target
IL36RN / IL1F5 (63)
Reactivity
Human (49)
Mouse (23)
Rat (8)
Bovine (4)
Cow (1)
Dog (4)
Gibbon (6)
Monkey (4)
Application
IHC (9)
IHC-P (2)
WB (55)
ELISA (28)
IF (1)
Host
rabbit (61)
mouse (2)
Isotype
IgG (22)
IgG1 (1)
Clonality
monoclonal mc (2)
polyclonal pc (61)
Format
AP Conjugated (1)
APC (3)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (8)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (4)
Unconjugated (26)
Epitope
aa12-151 (16)
C-Terminus (8)
aa1-156 (8)
aa76-104 (7)
aa1-155 (5)
Internal (1)
Publications
No (63)
Showing 1-25 of 63 results

IHC-plus™ IL36RN / IL1F5 Antibody LS-B10137
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-IL36RN / IL1F5 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Immunofluorescence of IL-36RN in rat small intestine tissue with IL-36RN antibody at 20 ug/ml.

IL36RN / IL1F5 Antibody (aa76-104) LS-C329673
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, IHC, WB
Unconjugated
200µl  $530.00

IL36RN / IL1F5 Antibody (aa76-104, Biotin) LS-C236549
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $680.00

IL36RN / IL1F5 Antibody (aa76-104, FITC) LS-C236550
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, IHC, WB
FITC Conjugated
200µl  $680.00

IL36RN / IL1F5 Antibody (aa76-104, AP) LS-C236544
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, IHC, WB
AP Conjugated
200µl  $680.00

IL36RN / IL1F5 Antibody (aa76-104, APC) LS-C236548
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, IHC, WB
APC Conjugated
200µl  $680.00

IL36RN / IL1F5 Antibody (aa76-104, PE) LS-C236551
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, IHC, WB
PE Conjugated
200µl  $680.00

IL36RN / IL1F5 Antibody (aa76-104, Azide-free, HRP) LS-C249260
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $680.00

IL36RN / IL1F5 Antibody (aa1-155) LS-C379419
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, IHC, IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human skin tissue using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human colon cancer using antibody at 1:100 dilution.

IL36RN / IL1F5 Antibody LS-C666391
Mouse Monoclonal (IgG1) to Human IL36RN / IL1F5
Human
ELISA, WB
Unconjugated
100µg  $375.00

IL36RN / IL1F5 Antibody LS-C666392
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, WB
Unconjugated
100µg  $375.00

IL36RN / IL1F5 Antibody LS-C743251
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Mouse, Rat, Human
ELISA, WB
Unconjugated
50µg 1mg/ml  $265.00; 100µg 1mg/ml  $325.00

IL36RN / IL1F5 Antibody LS-C767529
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Mouse, Rat, Human
ELISA, WB
Unconjugated
20µl 1mg/ml  $205.00; 60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

IL36RN / IL1F5 Antibody LS-C804126
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Mouse, Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Western blot Image

IL36RN / IL1F5 Antibody (aa1-155) LS-C372068
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Western blot All lanes: IL36RN antibody at 16µg/ml + Mouse stomach tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 17 kDa Observed band size: 17 kDa
Western Blot Positive WB detected in: Rat kidney tissue All lanes: IL36RN antibody at 3.2µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 17 kDa Observed band size: 17 kDa

IL36RN / IL1F5 Antibody (aa1-155, HRP) LS-C372074
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, WB
HRP Conjugated
50µg  $285.00; 100µg  $385.00

IL36RN / IL1F5 Antibody (aa1-155, Biotin) LS-C372072
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

IL36RN / IL1F5 Antibody (aa1-155, FITC) LS-C372073
Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5
Human
ELISA, WB
FITC Conjugated
50µg  $285.00; 100µg  $385.00

IL36RN / IL1F5 Antibody LS-C745949
Rabbit Polyclonal (IgG) to Bovine IL36RN / IL1F5
Bovine
ELISA, WB
Unconjugated
0.1mg  $445.00

IL36RN / IL1F5 Antibody LS-C154077
Rabbit Polyclonal (IgG) to Bovine IL36RN / IL1F5
Bovine
ELISA, WB
Unconjugated
100µg 1mg/ml  $425.00
Anti-Bovine IL-1F5 Antibody - Western Blot. Western blot of Protein-A Purified anti-bovine IL-1F5 antibody shows detection of recombinant bovine IL-1F5 at 17.1 kD (arrowhead) raised in yeast. The identity of the band at 36 kD is not known. The protein was purified and resolved by SDS-PAGE, then transferred to PVDF membrane. Membrane was blocked with 3% BSA (BSA-30, diluted 1:10), and probed with 1 ug/mL primary antibody overnight at 4C. After washing, membrane was probed with IRDye800 Conjugated Goat Anti-Rabbit IgG ( for 45 min at room temperature.

IL36RN / IL1F5 Antibody LS-C745207
Rabbit Polyclonal (IgG) to Bovine IL36RN / IL1F5
Bovine, Cow
ELISA, WB
Unconjugated
25µl 1mg/ml  $235.00
Western blot using the Protein-A Purified anti-bovine IL-1F5 antibody shows detection of recombinant bovine IL-1F5 at 17.1 kDa (arrowhead) raised in yeast. The identity of the band at 36 kDa is not known. The protein was purified and resolved by SDS-PAGE, then transferred to PVDF membrane. Membrane was blocked with 3% BSA (BSA-30, diluted 1:10), and probed with 1 µg/mL primary antibody overnight at 4°C. After washing, membrane was probed with for 45 min at room temperature.

IL36RN / IL1F5 Antibody LS-C487449
Rabbit Polyclonal to Mouse IL36RN / IL1F5
Mouse
ELISA
Unconjugated
50µl  $275.00; 100µl  $355.00

IL36RN / IL1F5 Antibody LS-C487450
Rabbit Polyclonal to Mouse IL36RN / IL1F5
Mouse
ELISA
Unconjugated
100µl  $255.00; 200µl  $305.00; 400µl  $355.00

IL36RN / IL1F5 Antibody LS-C487446
Mouse Monoclonal to Human IL36RN / IL1F5
Human
ELISA
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

IL36RN / IL1F5 Antibody (aa1-156) LS-C314543
Rabbit Polyclonal to Mouse IL36RN / IL1F5
Mouse
WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $485.00
Western blot of recombinant IL36RN / IL1F5.
Showing 1-25 of 63 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).