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IL18BP

interleukin 18 binding protein

IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: interleukin 18 binding protein
Family/Subfamily: Interleukin
Synonyms: IL18BP, IL18BPa, Interleukin-18-binding protein, Interleukin 18 binding protein, Tadekinig-alfa, IL-18BP
Target Sequences: NM_173042 NP_766630.2 O95998

☰ Filters
Products
Proteins (22)
Over-Expression Lysate (8)
Recombinant (14)
IL18BP (22)
No (22)
6His, N-terminus (1)
Fc, C-terminus (4)
GST (1)
His (4)
His, N-Terminal (1)
Myc-DDK (Flag) (8)
Human (12)
Mouse (5)
Rat (1)
293T Cells (4)
CHO Cells (1)
E. coli (7)
HEK 293 Cells (5)
Human Cells (2)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (7)
Biologically active (1)
IL18BP Protein - Recombinant Interleukin 18 Binding Protein By SDS-PAGE
Select
E. coli
His, N-Terminal
19.5 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
IL18BP Protein
Select
E. coli
6His, N-terminus
22.1 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
HEK 293 Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
~19 kDa
200 µg/$975
IL18BP Protein
Select
E. coli
His
19.1 kDa
10 µg/$277; 50 µg/$415; 100 µg/$662; 200 µg/$830; 1 mg/$1,916; 500 µg/$1,465; 5 mg/$2,899; 2 mg/$2,101
IL18BP Protein - Recombinant Interleukin 18 Binding Protein By SDS-PAGE
Select
E. coli
His
19.4 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
IL18BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
21.1 kDa
100 µg/$494
IL18BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
17.8 kDa
100 µg/$494
IL18BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
21.1 kDa
100 µg/$494
IL18BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
21.1 kDa
100 µg/$494
Select
E. coli
His
20.6 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
IL18BP Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
42-44 kDa (SDS-PAGE)
50 µg/$296; 10 µg/$253; 1 mg/$1,470
IL18BP Protein - 12.5% SDS-PAGE of human IL18BP stained with Coomassie Blue
Select
Wheat Germ Extract
GST
43.78 kDa
10 µg/$479; 25 µg/$670
IL18BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.1 kDa
20 µg/$150
IL18BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.1 kDa
20 µg/$150
IL18BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.1 kDa
20 µg/$150
IL18BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
17.8 kDa
20 µg/$150
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
~19 kDa
1 mg/$3,329
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
45.1 kDa
10 µg/$259; 50 µg/$317
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.7 kDa
10 µg/$244; 50 µg/$288
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.7kD
10 µg/$243; 50 µg/$288; 500 µg/$785; 1 mg/$1,021
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
45.1kD
10 µg/$258; 50 µg/$321; 500 µg/$1,262; 1 mg/$1,627
Viewing 1-22 of 22 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).