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IL18

interleukin 18 (interferon-gamma-inducing factor)

Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.

Gene Name: interleukin 18 (interferon-gamma-inducing factor)
Family/Subfamily: IL-1 , not assigned-IL-1
Synonyms: IL18, IGIF, IL-1g, Interleukin-18, IFN-gamma-inducing factor, IL-1 gamma, IL-18, Iboctadekin, IL1F4, Interleukin-1 gamma
Target Sequences: NM_001562 NP_001553.1 Q14116

Publications (5)

1
USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation. Palazón-Riquelme P, Worboys JD, Green J, Valera A, Martín-Sánchez F, Pellegrini C, Brough D, López-Castejón G. EMBO reports. 2018 October;19:pii e44766. [Full Text Article] [PubMed:30206189] [PMC:PMC6172458] Related Antibodies: LS-C313397.
2
High Levels of IL-18 and IFN-? in Chronically Inflamed Tissue in Chronic Granulomatous Disease. Meda Spaccamela V, Valencia RG, Pastukhov O, Duppenthaler A, Dettmer MS, Erb J, Steiner UC, Hillinger S, Speckmann C, Ehl S, Reichenbach J, Siler U. Frontiers in immunology. 2019 October;10: [Full Text Article] [PubMed:31681257] [PMC:PMC6813411] Related Antibodies: LS-C313164.
3
Mincle/Syk signaling promotes intestinal mucosal inflammation through induction of macrophage pyroptosis in Crohn's disease. Wenbin Gong, Tao Zheng, Guo Kun, Fang Miao, Haohao Xie, Li Weijie, Qinqing Tang, Zhiwu Hong, Huajian Ren, Guosheng Gu, Gefei Wang, Xiuwen Wu, Yun Zhao, Jianan Ren. Journal of Crohn's & colitis. 2020 April; [Full Text Article] [PubMed:32333776] Related Antibodies: LS-C754834.
4
Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro. Anna Gritsenko, Shi Yu, Fatima Martin-Sanchez, Ines Diaz-Del-Olmo, Eva-Maria Nichols, Daniel M Davis, David Brough, Gloria Lopez-Castejon. Frontiers in immunology. 2020 October;11:565924. [Full Text Article] [PubMed:33101286] [PMC:PMC7555430] Related Antibodies: LS-C313397.
5
Melatonin attenuates smoking-induced atherosclerosis by activating the Nrf2 pathway via NLRP3 inflammasomes in endothelial cells. Zhewei Zhao, Xuebin Wang, Rui Zhang, Baitao Ma, Shuai Niu, Xiao Di, Leng Ni, Changwei Liu. Aging. 2021 Apr;13:11363-11380. [Full Text Article] [PubMed:33839695] [PMC:PMC8109127]
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ELISA Kits (59)
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IL18 (59)
Human (13)
Mouse (9)
Rat (12)
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Dog (3)
Guinea pig (2)
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Coronavirus Detection (58)
Cytokine Release Syndrome (58)
DevKit DuoPlus (4)
ELISA Kits for Cytokine Release Syndrome Targets (58)
12 x 8-Well Microstrips (2)
96-Well Microplate (12)
96-Well Strip Plate (41)
Antibody Pair and Standard (4)
No (59)
Cell Culture Supernatants (26)
Cell Lysates (15)
Plasma (53)
Serum (53)
Tissue Homogenates (26)
Urine (4)
IL18 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$863
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
IL18 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.5 - 75 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
39 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$579
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Canine
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$814
IL18 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IL18 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.205 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$700
IL18 ELISA Kit
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Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates, Urine
1 Plate/$734
IL18 ELISA Kit
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Sandwich
96-Well Microplate
Pig
81.92 - 20000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$441
IL18 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
IL18 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
2.74 - 2000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$1,034
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
IL18 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL18 ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$685
IL18 ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
IL18 ELISA Kit
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Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
IL18 ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).