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Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.
Gene Name: | interleukin 17 receptor E |
Family/Subfamily: | Interleukin |
Synonyms: | IL17RE, IL-17RE, IL-17 receptor E, Interleukin 17 receptor E, Interleukin-17 receptor E |
Target Sequences: | NM_153480 NP_705613.1 Q8NFR9 |
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