IL17C

interleukin 17C

Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.

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Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

IL17C (7)

Publications

No (7)

Tag

GST (1)

His, N-Terminal (1)

His-GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human IL17C Protein (Recombinant His-GST, N-terminus) - LS-G15248

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

20.7 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Rat IL17C Protein (Recombinant His, N-Terminal) (His23-Gln203) - LS-G133222

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

23.9kDa

Price:

10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human IL17C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89794

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.6 kDa

Price:

20 µg/$150

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IL17C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114353

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.6 kDa

Price:

100 µg/$494

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Human IL17C Protein (Recombinant GST) (Full Length) - LS-G33287

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.2 kDa

Price:

2 µg/$439

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Human IL17C Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71449

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.6 kDa

Price:

20 µg/$1,107

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Mouse IL17C Protein (Recombinant His-T7) (aa7-159) - LS-G15250

Source:

E. coli

Tag:

His-T7

Molecular Weight:

21.0 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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