IKBKG / NEMO / IKK Gamma

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.

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Products

ELISA Kits (9)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (3)

Sandwich (3)

Target

IKBKG / NEMO / IKK Gamma (9)

Reactivity

Human (6)

Mouse (1)

Rat (1)

Format

96-Well Microplate (3)

96-Well Strip Plate (6)

Publications

No (9)

Sample Type

Adherent Cell Cultures (3)

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

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Human IKBKG / NEMO / IKK Gamma (Sandwich ELISA) ELISA Kit - LS-F12135

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rat IKBKG / NEMO / IKK Gamma (Custom ELISA) ELISA Kit - LS-F20600

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse IKBKG / NEMO / IKK Gamma (Custom ELISA) ELISA Kit - LS-F20599

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Bovine IKBKG / NEMO / IKK Gamma (Custom ELISA) ELISA Kit - LS-F20601

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human IKBKG / NEMO / IKK Gamma (Sandwich ELISA) ELISA Kit - LS-F34028

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human IKBKG / NEMO / IKK Gamma (Sandwich ELISA) ELISA Kit - LS-F55046

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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Human Phospho-IKBKG / NEMO / IKK Gamma (Ser85) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1418

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Human IKBKG / NEMO / IKK Gamma (Cell-Based ELISA) ELISA Kit - LS-F2073

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Human Phospho-IKBKG / NEMO / IKK Gamma (Ser31) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1145

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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