IGHD

Immunoglobulin Heavy Constant Delta

IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.

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Products

Antibodies (8)

Type

Primary (8)

Target

IGHD (8)

Reactivity

Human (8)

Application

IHC (2)

WB (2)

ELISA (6)

IHC-Fx (2)

SDS-PAGE (2)

Host

rabbit (7)

goat (1)

Isotype

IgG (8)

Clonality

polyclonal pc (6)

recombinant monoclonal rmc (2)

Clone

IGHD/2730R (2)

Format

Azide-free (1)

Biotin Conjugated (2)

Carrier-free (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (4)

Publications

No (8)

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IGHD Antibody LS-C682202

Antibody:

IGHD Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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IGHD Antibody (HRP) LS-C678294

Antibody:

IGHD Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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IGHD Antibody (Biotin) LS-C678292

Antibody:

IGHD Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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IGHD Antibody (FITC) LS-C682203

Antibody:

IGHD Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IGHD Antibody LS-C666343

Antibody:

IGHD Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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IGHD Antibody (clone IGHD/2730R) LS-C751188

Antibody:

IGHD Rabbit anti-Human Recombinant Monoclonal (IGHD/2730R) Antibody

Reactivity:

Human

Applications:

IHC-Fx, SDS-PAGE

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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IGHD Antibody (clone IGHD/2730R, Azide-free, Carrier-free) LS-C751189

Antibody:

IGHD Rabbit anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (IGHD/2730R) Antibody

Reactivity:

Human

Applications:

IHC-Fx, SDS-PAGE

Format:

Unconjugated, Azide-free, Carrier-free

Price:

100 µg/$574

• Unconjugated
• Unconjugated, Azide-free, Carrier-free

• Unconjugated
• Unconjugated, Azide-free, Carrier-free

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IGHD Antibody (Biotin) LS-C745733

Antibody:

IGHD Goat anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

0.5 mg/$374

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