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IGF2AS expresses a paternally imprinted antisense transcript of the insulin-like growth factor 2 gene. The transcript is overexpressed in Wilms' tumor. This gene is predicted to be non-coding because the predicted protein is not conserved in any other species and the majority of transcripts would be candidates for non-sense mediated decay (NMD) if a protein were expressed. Alternative splicing results in multiple transcript variants.
Gene Name: | IGF2 antisense RNA |
Synonyms: | IGF2-AS, C11orf43, IGF2-AS1, IGF-II, IGF2 antisense RNA, IGF2AS, PEG8, PP9974, Somatomedin-A |
Target Sequences: | NM_016412 NP_057496.2 Q6U949 |
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