IFNL2 / IL28A

interferon, lambda 2

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

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Products

ELISA Kits (14)

Type

Development Kit (1)

Sandwich (11)

Sandwich CLIA (2)

Target

IFNL2 / IL28A (14)

Reactivity

Human (11)

Mouse (3)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (10)

Antibody Pair and Standard (1)

Publications

No (14)

Sample Type

Cell Culture Supernatants (6)

Cell Lysates (5)

Plasma (13)

Serum (13)

Tissue Homogenates (5)

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F4909

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

7.81 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

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Mouse IFNL2 / IL28A (CLIA) ELISA Kit - LS-F26272

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.37 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$990

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F645

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$618

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F2796

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$795

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F24573

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$669

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Human IFNL2 / IL28A (CLIA) ELISA Kit - LS-F26271

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.37 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$968

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F38146

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F32555

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F54939

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$864

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DevKit DuoPlus Human IFNL2 / IL28A ELISA Development Kit - LS-F71746

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

3.12 - 200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,229; 1000 Wells/$1,826

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Mouse IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F8158

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$818

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F11773

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F11774

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$685

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F123

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

13.71 - 3333 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$588

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