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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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IFI30 / IP30
Interferon, Gamma-inducible Protein 30
Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds (By similarity). Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation.
| Gene Name: | Interferon, Gamma-inducible Protein 30 |
| Synonyms: | IFI30, GILT, Legumaturain, IFI-30, IP30 |
| Target Sequences: | NM_006332 NP_006323.2 P13284 |
Publications (1)
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