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ICT1 / DS1

immature colon carcinoma transcript 1

Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

Gene Name:	immature colon carcinoma transcript 1
Synonyms:	ICT1, Digestion substraction 1, DS1, DS-1
Target Sequences:	NM_001545 NP_001536.1 Q14197

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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