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ICMT / PPMT

isoprenylcysteine carboxyl methyltransferase

ICMT / PPMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

Gene Name:	isoprenylcysteine carboxyl methyltransferase
Synonyms:	ICMT, MSTP098, HSTE14, PPMT, MST098, PCCMT, PCMT
Target Sequences:	AF064084 AAC16554.1 O60725

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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