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Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified.
Gene Name: | FIC domain containing |
Synonyms: | FICD, AMPylator FICD, FIC domain containing, FIC domain-containing protein, HIP13, Huntingtin yeast partner E, UNQ3041, HIP-13, HYPE |
Target Sequences: | NM_007076 NP_009007.2 Q9BVA6 |
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